Theory of thoughts (ToM), or the capacity to attribute psychological states to oneself and others, is a core factor of social cognition (SC). Even although its significance for social functioning usually, and neurodevelopmental problems (NDDs), specifically, is nicely established, the hyperlinks between ToM and different cognitive features usually are not. Especially the familial underpinnings of such hyperlinks stay unclear.
Using a co-twin management design, we examined N = 311 twins (imply age M = 17.19 years, 47% females) recognized with autism spectrum dysfunction (ASD), consideration-deficit/hyperactivity dysfunction (ADHD), different NDDs, or sometimes growing people. We used the Reading the Mind in the Eyes Test to operationalize ToM, the Fragmented Pictures Test for central coherence (CC), the Tower Test for govt functioning (EF), and the normal capacity index in the Wechsler Intelligence Scales for IQ.
In the linear regressions, weak CC and a decrease IQ have been related to a decreased ToM capacity throughout pairs. Female intercourse and larger age have been robustly related to elevated ToM capacity, whereas EF was not related to ToM. In the inside-pair analyses, the place unmeasured familial confounders are implicitly adjusted, the associations between ToM and different cognitive features, have been attenuated and the affiliation with CC was non-important.
The end result means that familial elements shared by the twins, reminiscent of genetic and shared setting, affect the affiliation between CC, IQ, and ToM. Future research want to incorporate a bigger pattern of monozygotic twins, who’re genetically similar, with the intention to draw extra agency conclusions relating to the affect of familial elements, and to distinguish between shared environmental and genetic results on the associations between cognitive features.
Safety and Efficacy of Intravenous Ferric Derisomaltose Compared to Iron Sucrose for Iron Deficiency Anemia in Patients with Chronic Kidney Disease With and Without Heart Failure
Ferric derisomaltose (FDI) is an intravenous (IV) excessive-dose iron formulation authorised in the US for the remedy of iron deficiency anemia in adults who’re illiberal of/have had an unsatisfactory response to oral iron, or who’ve non-dialysis-dependent continual kidney illness (NDD-CKD). FERWON-NEPHRO was a randomized, open-label, multicenter scientific trial evaluating the security and efficacy of a single infusion of FDI 1,000 mg versus as much as 5 doses of iron sucrose (IS) 200 mg (advisable cumulative dose, 1,000 mg) over eight weeks in sufferers with NDD-CKD and iron deficiency anemia. Of 1,525 sufferers included in the security evaluation, 244 (16%) had a historical past of coronary heart failure (HF).
Overall, the price of critical or extreme hypersensitivity reactions was low and didn’t differ between remedy teams. Cardiovascular hostile occasions (AEs) have been reported for 9.4% of sufferers who had HF and 4.2% who didn’t. Time to first cardiovascular AE was longer following administration of FDI in contrast with IS (hazard ratio: 0.59 [95% CI: 0.37, 0.92]; p=0.0185), a distinction that was comparable in sufferers with or with out HF (p=0.908 for interplay).

Patients achieved a sooner hematological response (assessed by adjustments in hemoglobin and ferritin concentrations, and improve in transferrin saturation) with FDI versus IS. In conclusion, in sufferers with NDD-CKD, a single infusion of FDI was secure, nicely tolerated, and was related to fewer cardiovascular AEs and a sooner hematological response, in comparison with a number of doses of IS. These results have been comparable for sufferers with and with out HF.
Further proof for de novo variants in SYNCRIP as the trigger of a neurodevelopmental dysfunction
SYNCRIP encodes for the Synaptotagmin-binding cytoplasmic RNA-interacting protein, concerned in RNA-binding and regulation of a number of mobile pathways. It has been proposed as a candidate gene for neurodevelopmental problems (NDDs) with autism spectrum dysfunction (ASD), mental incapacity (ID), and epilepsy. We ascertained genetic, scientific, and neuroradiological information of three further people with novel de novo SYNCRIP variants.
All people had ID. Autistic options have been noticed in two. One particular person confirmed myoclonic-atonic epilepsy. Neuroradiological options comprised periventricular nodular heterotopia and widening of subarachnoid areas. Two frameshift variants in the extra severely affected people, seemingly end in haploinsufficiency.
The third missense variant lies in the conserved RRM 2 area seemingly affecting RNA-binding. Our findings assist the significance of RRM domains for SYNCRIP performance and counsel genotype-phenotype correlations. Our research supplies additional proof for an SYNCRIP-related NDD characterised by ID and ASD sporadically accompanied by malformations of cortical growth and myoclonic-atonic epilepsy.
Check This One: Rat Tumor Necrosis Factor (TNF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Tumor Necrosis Factor (TNF) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. Get More Information: abx050220
Neurodegenerative Disease Risk in Carriers of Autosomal Recessive Disease
Genetics has pushed important discoveries in the area of neurodegenerative illnesses (NDDs). An rising theme in neurodegeneration warrants an pressing and complete replace: that provider standing of early-onset autosomal recessive (AR) illness, sometimes thought-about benign, is related to an elevated threat of a spectrum of late-onset NDDs.
Glucosylceramidase beta (GBA1) gene mutations, liable for the AR lysosomal storage dysfunction Gaucher illness, are a outstanding instance of this precept, having been recognized as an necessary genetic threat issue for Parkinson illness. Genetic analyses have revealed additional examples, notably GRN, TREM2, EIF2AK3, and a number of different LSD and mitochondria perform genes.
DcR2 Antibody |
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E300301 | EnoGene | 100ug/200ul | 275 EUR |
Description: Available in various conjugation types. |
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DcR2 Antibody |
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E90184 | EnoGene | 100ul | 255 EUR |
Description: Available in various conjugation types. |
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DcR2 Antibody |
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MBS151536-01mg | MyBiosource | 0.1mg | 445 EUR |
DcR2 Antibody |
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MBS151536-5x01mg | MyBiosource | 5x0.1mg | 1965 EUR |
DcR2 Antibody |
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MBS8506050-01mL | MyBiosource | 0.1mL | 325 EUR |
DcR2 Antibody |
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MBS8506050-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
DcR2 Antibody |
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MBS8506050-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
DcR2 Antibody |
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MBS8506050-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
DcR2 Antibody |
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MBS8506050-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
DcR2 Antibody |
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MBS853411-01mg | MyBiosource | 0.1mg | 345 EUR |
DcR2 Antibody |
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MBS853411-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
DcR2 Antibody |
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MBS853411-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
DcR2 Antibody |
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MBS853411-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
DcR2 Antibody |
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MBS853411-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
DcR2 Antibody |
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MBS9411384-01mL | MyBiosource | 0.1mL | 495 EUR |
DcR2 Antibody |
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MBS9411384-5x01mL | MyBiosource | 5x0.1mL | 2075 EUR |
DcR2 monoclonal antibody |
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MB10820 | Bioworld Biotech | 50ul | 398 EUR |
Description: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
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Rabbit Polyclonal DcR2 Antibody |
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TA305975 | Origene Technologies GmbH | 100 µg | Ask for price |
DcR2 Rabbit Monoclonal Antibody |
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E10G21303 | EnoGene | 100 μl | 275 EUR |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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DCR2 Rabbit Monoclonal Antibody |
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E46F1834 | EnoGene | 40ul | 225 EUR |
DcR2 (2U6) Rabbit Monoclonal Antibody |
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E28M0936 | EnoGene | 100ul | 295 EUR |
DCR2 (3Q13) Rabbit Monoclonal Antibody |
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E28M6350 | EnoGene | 100ul | 295 EUR |
DcR2 (TNFRSF10D) goat polyclonal antibody |
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GT15063-100 | Origene Technologies GmbH | 100 µg | Ask for price |
Human DcR2/TRAIL R4 Antibody Pair Set |
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ABPR-ZB173 | Creative Diagnostics | 5 plates, 15 plates | Ask for price |
Description: Quantitative determination of Human DcR2/TRAIL R4 |
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Mouse Anti-Human DcR2/TRAIL R4 monoclonal antibody, clone NN19 |
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CABT-ZB595 | Creative Diagnostics | 50 μl | 456 EUR |
Description: Mouse |
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Mouse Anti-Human DcR2/TRAIL R4 monoclonal antibody, clone NN10 |
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CABT-ZB947 | Creative Diagnostics | 50 μl | 456 EUR |
Description: Mouse |
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DcR2 (TNFRSF10D) rabbit polyclonal antibody, Purified |
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SP1174P | Origene Technologies GmbH | 100 µg | Ask for price |
DcR2/TRAIL R4 Matched ELISA Antibody Pair Set, Human |
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MBS8118246-15Plates | MyBiosource | 15Plates | 800 EUR |
DcR2/TRAIL R4 Matched ELISA Antibody Pair Set, Human |
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MBS8118246-5Plates | MyBiosource | 5Plates | 450 EUR |
DcR2/TRAIL R4 Matched ELISA Antibody Pair Set, Human |
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MBS8118246-5x15Plates | MyBiosource | 5x15Plates | 3695 EUR |
DcR2 (TNFRSF10D) (Center) rabbit polyclonal antibody, Aff - Purified |
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AP54308PU-N | Origene Technologies GmbH | 400 µl | Ask for price |
DcR2 (TNFRSF10D) mouse monoclonal antibody, clone B-R27, PE |
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AM31202RP-N | Origene Technologies GmbH | 1 ml (100 Tests) | Ask for price |
DcR2 (TNFRSF10D) mouse monoclonal antibody, clone B-R27, Purified |
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AM31202PU-N | Origene Technologies GmbH | 2 ml (200 Tests) | Ask for price |
DcR2 Peptide |
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2021P | ProSci | 0.05 mg | 197.7 EUR |
Description: (ID) DcR2 peptide |
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DcR2 Peptide |
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MBS152842-005mg | MyBiosource | 0.05mg | 175 EUR |
DcR2 Peptide |
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MBS152842-5x005mg | MyBiosource | 5x0.05mg | 770 EUR |
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) DCR2 Polyclonal Antibody |
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MBS9017504-INQUIRE | MyBiosource | INQUIRE | Ask for price |
DcR2 (TNFRSF10D) mouse monoclonal antibody, clone B-P30, Azide Free |
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AM31201AF-N | Origene Technologies GmbH | 200 µg | Ask for price |
DcR2 (TNFRSF10D) mouse monoclonal antibody, clone TRAIL-R4-01, PE |
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AM03039RP-N | Origene Technologies GmbH | 100 µg | Ask for price |
DcR2 (TNFRSF10D) mouse monoclonal antibody, clone TRAIL-R4-01, FITC |
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AM03039FC-N | Origene Technologies GmbH | 100 µg | Ask for price |
DcR2 (TNFRSF10D) mouse monoclonal antibody, clone TRAIL-R4-01, Azide Free |
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AM03039AF-N | Origene Technologies GmbH | 100 µg | Ask for price |
Anti-DcR2 Antibody |
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2419 | Genovis AB | 100ug | 445 EUR |
Anti-DcR2 Antibody |
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MBS194060-01mg | MyBiosource | 0.1mg | 495 EUR |
Anti-DcR2 Antibody |
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MBS194060-5x01mg | MyBiosource | 5x0.1mg | 2215 EUR |
Anti-DcR2 antibody |
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PAab02271 | Lifescience Market | 100 ug | 494.4 EUR |
Anti-DcR2 Antibody |
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Y080031 | ABM | 100 µl | 125 EUR |
DCR2 Rabbit mAb |
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A3581 | Abclonal | 100μL | 343.62 EUR |
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human RPL7A (P62424). |
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DcR2 Rabbit mAb |
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52249 | SAB | 100ul | 499 EUR |
DCR2 Rabbit mAb |
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60008 | SAB | 100ul | 339 EUR |
DcR2 Rabbit mAb |
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E2R24086 | EnoGene | 100ul | 255 EUR |
Description: Available in various conjugation types. |
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DcR2 Rabbit mAb |
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E2R389166 | EnoGene | 100ul | 275 EUR |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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DcR2 Rabbit pAb |
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E47R1694 | EnoGene | 100ul | 295 EUR |
DCR2 Rabbit mAb |
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E45R11528N | EnoGene | 50 ul | 346.5 EUR |
DcR2 Rabbit mAb |
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MBS4752697-01mL | MyBiosource | 0.1mL | 450 EUR |
DcR2 Rabbit mAb |
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MBS4752697-5x01mL | MyBiosource | 5x0.1mL | 1540 EUR |
DcR2 Rabbit mAb |
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MBS9466962-005mL | MyBiosource | 0.05mL | 290 EUR |
DcR2 Rabbit mAb |
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MBS9466962-01mL | MyBiosource | 0.1mL | 435 EUR |
DcR2 Rabbit mAb |
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MBS9466962-5x01mL | MyBiosource | 5x0.1mL | 1810 EUR |
DcR2 ELISA KIT|Human |
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EF009028 | Lifescience Market | 96 Tests | 826.8 EUR |
DcR2 Recombinant Rabbit mAb |
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BS46193 | Bioworld Biotech | 50 ul | 398 EUR |
Description: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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Anti-DcR2 TNFRSF10D Antibody |
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A05136-1 | BosterBio | 0.1mg | 449 EUR |
Description: Boster Bio Anti-DcR2 TNFRSF10D Antibody (Catalog # A05136-1). Tested in ELISA, WB, ICC, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat. |
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Recombinant Human DcR2 Protein |
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MBS9141853-002mg | MyBiosource | 0.02mg | 165 EUR |
Recombinant Human DcR2 Protein |
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MBS9141853-005mg | MyBiosource | 0.05mg | 195 EUR |
Recombinant Human DcR2 Protein |
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MBS9141853-01mg | MyBiosource | 0.1mg | 250 EUR |
Recombinant Human DcR2 Protein |
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MBS9141853-5x01mg | MyBiosource | 5x0.1mg | 945 EUR |
Anti-DCR2 Rabbit Monoclonal Antibody |
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1834-100uL | Gene Universal | 100 μL | 329 EUR |
Anti-DCR2 Rabbit Monoclonal Antibody |
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1834-20uL | Gene Universal | 20 μL | 129 EUR |
Anti-DCR2 Rabbit Monoclonal Antibody |
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M05136-2 | BosterBio | 30ul | 154 EUR |
Description: WB 1:500-1:2000;IHC 1:50-1:200;ICC/IF 1:50-1:200 |
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human Trail Receptor 4/DcR2/CD264 |
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M850850048 | Tecan Benelux | 1 unit | 267.03 EUR |
Human DCR2/TNFRSF10D PicoKine ELISA Kit |
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MBS1752672-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 2755 EUR |
Human DCR2/TNFRSF10D PicoKine ELISA Kit |
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MBS1752672-96StripWells | MyBiosource | 96-Strip-Wells | 600 EUR |
Human DcR2 (Decoy receptor 2) ELISA Kit |
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MBS7615303-10x96StripWells | MyBiosource | 10x96-Strip-Wells | 3900 EUR |
Human DcR2 (Decoy receptor 2) ELISA Kit |
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MBS7615303-48StripWells | MyBiosource | 48-Strip-Wells | 340 EUR |
Human DcR2 (Decoy receptor 2) ELISA Kit |
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MBS7615303-5x96StripWells | MyBiosource | 5x96-Strip-Wells | 2045 EUR |
Human DcR2 (Decoy receptor 2) ELISA Kit |
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MBS7615303-96StripWells | MyBiosource | 96-Strip-Wells | 455 EUR |
Recombinant Human DcR2 Protein, Fc & His Tag |
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E40KMP1006 | EnoGene | 20ug | 495 EUR |
anti-DcR2 |
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YF-PA25185 | Abfrontier | 50 ul | 400.8 EUR |
Description: Mouse polyclonal to DcR2 |
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Human DCR2/TNFRSF10D ELISA Kit PicoKine® |
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EK2067 | BosterBio | 96 wells | 499 EUR |
Description: Human DCR2/TNFRSF10D ELISA Kit PicoKine® (96 Tests). Quantitate Human TNFRSF10D in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml. |
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Anti-B. anthracis Protective Antigen Monoclonal antibody, Clone DCR0203 |
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DMABT-Z59226 | Creative Diagnostics | 1 mg | 926.1 EUR |
Description: Mouse |
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DcR2 (TNFRSF10D) (NM_003840) Human Over-expression Lysate |
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E45H19123-2 | EnoGene | 20 ug | 395 EUR |
DcR2 (TNFRSF10D) (NM_003840) Human Over-expression Lysate |
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LS008793 | BosterBio | 100ug | 628 EUR |
Description: Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D) |
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Human DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8113831-03mg | MyBiosource | 0.3mg | 280 EUR |
Human DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8113831-5x03mg | MyBiosource | 5x0.3mg | 1205 EUR |
Human DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8113833-03mg | MyBiosource | 0.3mg | 280 EUR |
Human DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8113833-5x03mg | MyBiosource | 5x0.3mg | 1205 EUR |
Rhesus DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8117808-03mg | MyBiosource | 0.3mg | 280 EUR |
Rhesus DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8117808-5x03mg | MyBiosource | 5x0.3mg | 1205 EUR |
Rhesus DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8117809-03mg | MyBiosource | 0.3mg | 280 EUR |
Rhesus DcR2/TRAIL R4 HEK293 Overexpression Lysate |
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MBS8117809-5x03mg | MyBiosource | 5x0.3mg | 1205 EUR |
DcR2/TRAIL R4 Protein, Human, Recombinant (His Tag) |
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E45H51276M2-100 | EnoGene | 100 ug | 694.69 EUR |
DcR2/TRAIL R4 Protein, Human, Recombinant (His Tag) |
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MBS8118629-01mg | MyBiosource | 0.1mg | 290 EUR |
DcR2/TRAIL R4 Protein, Human, Recombinant (His Tag) |
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MBS8118629-1mg | MyBiosource | 1mg | 1465 EUR |
DcR2/TRAIL R4 Protein, Human, Recombinant (His Tag) |
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MBS8118629-5x1mg | MyBiosource | 5x1mg | 6445 EUR |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc Tag) |
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E45K54199M4-100 | EnoGene | 100 ug | 694.69 EUR |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc Tag) |
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MBS8123548-01mg | MyBiosource | 0.1mg | 290 EUR |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc Tag) |
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MBS8123548-5x01mg | MyBiosource | 5x0.1mg | 1155 EUR |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His Tag) |
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MBS8123549-01mg | MyBiosource | 0.1mg | 395 EUR |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His Tag) |
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MBS8123549-1mg | MyBiosource | 1mg | 2175 EUR |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His Tag) |
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MBS8123549-5x1mg | MyBiosource | 5x1mg | 9625 EUR |
Anti-DcR2/TRAIL R4 Antibody, Mouse Monoclonal |
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MBS8102707-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Mouse Monoclonal |
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MBS8102707-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
Anti-DcR2/TRAIL R4 Antibody, Mouse Monoclonal |
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MBS8102708-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Mouse Monoclonal |
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MBS8102708-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
Anti-DcR2/TRAIL R4 Antibody, Mouse Monoclonal |
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MBS8102709-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Mouse Monoclonal |
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MBS8102709-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8102714-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8102714-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8102716-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8102716-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8102717-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8102717-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8113193-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8113193-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8113194-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-DcR2/TRAIL R4 Antibody, Rabbit Polyclonal |
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MBS8113194-5x01mL | MyBiosource | 5x0.1mL | 1200 EUR |
human Trail Receptor 4/DcR2/CD264 1 x 96 |
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M850850096 | Tecan Benelux | 1 unit | 492.85 EUR |
human Trail Receptor 4/DcR2/CD264 2 x 96 |
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M850850192 | Tecan Benelux | 1 unit | 791.27 EUR |
Recombinant Human TNFRSF10D/DcR2/TRAIL-R4/CD264 Protein |
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RP00992 | Abclonal | 10 μg | 102.73 EUR |
TNFRSF6B/DCR3 Rabbit anti-Human Polyclonal Antibody |
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MBS2402673-005mL | MyBiosource | 0.05mL | 615 EUR |
TNFRSF6B/DCR3 Rabbit anti-Human Polyclonal Antibody |
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MBS2402673-5x005mL | MyBiosource | 5x0.05mL | 2605 EUR |
DcR2/TRAIL R4 Protein, Human, Recombinant (ECD, hFc Tag) |
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E45H50416M4-100 | EnoGene | 100 ug | 694.69 EUR |
DcR2/TRAIL R4 Protein, Human, Recombinant (ECD, hFc Tag) |
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MBS8120254-01mg | MyBiosource | 0.1mg | 290 EUR |
DcR2/TRAIL R4 Protein, Human, Recombinant (ECD, hFc Tag) |
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MBS8120254-5x01mg | MyBiosource | 5x0.1mg | 1155 EUR |
DcR1 Antibody |
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2299-002mg | ProSci | 0.02 mg | 206.18 EUR |
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis. |
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DcR1 Antibody |
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2299-01mg | ProSci | 0.1 mg | 523.7 EUR |
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis. |
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DcR3 Antibody |
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24071 | SAB | 100ul | 479 EUR |
DcR3 Antibody |
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24071-100ul | SAB | 100ul | 468 EUR |
DcR1 Antibody |
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2179-002mg | ProSci | 0.02 mg | 206.18 EUR |
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis. |
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DcR1 Antibody |
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2179-01mg | ProSci | 0.1 mg | 523.7 EUR |
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis. |
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DcR3 Antibody |
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2140-002mg | ProSci | 0.02 mg | 206.18 EUR |
Description: DcR3 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues. |
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DcR3 Antibody |
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2140-01mg | ProSci | 0.1 mg | 523.7 EUR |
Description: DcR3 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues. |
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DcR1 Antibody |
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24079 | SAB | 100ul | 479 EUR |
DcR1 Antibody |
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24079-100ul | SAB | 100ul | 468 EUR |
In this Review, we talk about the proof supporting the strikingly distinct allele-dependent scientific phenotypes noticed in carriers of such gene mutations and its affect on the wider area of neurodegeneration.
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