What's the Link Between Theory of Mind and Other Cognitive Abilities - A Co-twin Control Design of Neurodevelopmental Disorders

What’s the Link Between Theory of Mind and Other Cognitive Abilities – A Co-twin Control Design of Neurodevelopmental Disorders

Theory of thoughts (ToM), or the capacity to attribute psychological states to oneself and others, is a core factor of social cognition (SC). Even although its significance for social functioning usually, and neurodevelopmental problems (NDDs), specifically, is nicely established, the hyperlinks between ToM and different cognitive features usually are not. Especially the familial underpinnings of such hyperlinks stay unclear.
Using a co-twin management design, we examined N = 311 twins (imply age M = 17.19 years, 47% females) recognized with autism spectrum dysfunction (ASD), consideration-deficit/hyperactivity dysfunction (ADHD), different NDDs, or sometimes growing people. We used the Reading the Mind in the Eyes Test to operationalize ToM, the Fragmented Pictures Test for central coherence (CC), the Tower Test for govt functioning (EF), and the normal capacity index in the Wechsler Intelligence Scales for IQ.
In the linear regressions, weak CC and a decrease IQ have been related to a decreased ToM capacity throughout pairs. Female intercourse and larger age have been robustly related to elevated ToM capacity, whereas EF was not related to ToM. In the inside-pair analyses, the place unmeasured familial confounders are implicitly adjusted, the associations between ToM and different cognitive features, have been attenuated and the affiliation with CC was non-important.
The end result means that familial elements shared by the twins, reminiscent of genetic and shared setting, affect the affiliation between CC, IQ, and ToM. Future research want to incorporate a bigger pattern of monozygotic twins, who’re genetically similar, with the intention to draw extra agency conclusions relating to the affect of familial elements, and to distinguish between shared environmental and genetic results on the associations between cognitive features.

Safety and Efficacy of Intravenous Ferric Derisomaltose Compared to Iron Sucrose for Iron Deficiency Anemia in Patients with Chronic Kidney Disease With and Without Heart Failure

Ferric derisomaltose (FDI) is an intravenous (IV) excessive-dose iron formulation authorised in the US for the remedy of iron deficiency anemia in adults who’re illiberal of/have had an unsatisfactory response to oral iron, or who’ve non-dialysis-dependent continual kidney illness (NDD-CKD). FERWON-NEPHRO was a randomized, open-label, multicenter scientific trial evaluating the security and efficacy of a single infusion of FDI 1,000 mg versus as much as 5 doses of iron sucrose (IS) 200 mg (advisable cumulative dose, 1,000 mg) over eight weeks in sufferers with NDD-CKD and iron deficiency anemia. Of 1,525 sufferers included in the security evaluation, 244 (16%) had a historical past of coronary heart failure (HF).
Overall, the price of critical or extreme hypersensitivity reactions was low and didn’t differ between remedy teams. Cardiovascular hostile occasions (AEs) have been reported for 9.4% of sufferers who had HF and 4.2% who didn’t. Time to first cardiovascular AE was longer following administration of FDI in contrast with IS (hazard ratio: 0.59 [95% CI: 0.37, 0.92]; p=0.0185), a distinction that was comparable in sufferers with or with out HF (p=0.908 for interplay).
 What's the Link Between Theory of Mind and Other Cognitive Abilities - A Co-twin Control Design of Neurodevelopmental Disorders
Patients achieved a sooner hematological response (assessed by adjustments in hemoglobin and ferritin concentrations, and improve in transferrin saturation) with FDI versus IS. In conclusion, in sufferers with NDD-CKD, a single infusion of FDI was secure, nicely tolerated, and was related to fewer cardiovascular AEs and a sooner hematological response, in comparison with a number of doses of IS. These results have been comparable for sufferers with and with out HF.

Further proof for de novo variants in SYNCRIP as the trigger of a neurodevelopmental dysfunction

SYNCRIP encodes for the Synaptotagmin-binding cytoplasmic RNA-interacting protein, concerned in RNA-binding and regulation of a number of mobile pathways. It has been proposed as a candidate gene for neurodevelopmental problems (NDDs) with autism spectrum dysfunction (ASD), mental incapacity (ID), and epilepsy. We ascertained genetic, scientific, and neuroradiological information of three further people with novel de novo SYNCRIP variants.
All people had ID. Autistic options have been noticed in two. One particular person confirmed myoclonic-atonic epilepsy. Neuroradiological options comprised periventricular nodular heterotopia and widening of subarachnoid areas. Two frameshift variants in the extra severely affected people, seemingly end in haploinsufficiency.
The third missense variant lies in the conserved RRM 2 area seemingly affecting RNA-binding. Our findings assist the significance of RRM domains for SYNCRIP performance and counsel genotype-phenotype correlations. Our research supplies additional proof for an SYNCRIP-related NDD characterised by ID and ASD sporadically accompanied by malformations of cortical growth and myoclonic-atonic epilepsy.
Check This One: Rat Tumor Necrosis Factor (TNF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Tumor Necrosis Factor (TNF) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. Get More Information: abx050220

Neurodegenerative Disease Risk in Carriers of Autosomal Recessive Disease

Genetics has pushed important discoveries in the area of neurodegenerative illnesses (NDDs). An rising theme in neurodegeneration warrants an pressing and complete replace: that provider standing of early-onset autosomal recessive (AR) illness, sometimes thought-about benign, is related to an elevated threat of a spectrum of late-onset NDDs.
Glucosylceramidase beta (GBA1) gene mutations, liable for the AR lysosomal storage dysfunction Gaucher illness, are a outstanding instance of this precept, having been recognized as an necessary genetic threat issue for Parkinson illness. Genetic analyses have revealed additional examples, notably GRN, TREM2, EIF2AK3, and a number of different LSD and mitochondria perform genes.

DcR2 Rabbit mAb

E2R24086 EnoGene 100ul 255 EUR
Description: Available in various conjugation types.

DCR2 Rabbit mAb

A3581 Abclonal 100μL 778.7 EUR
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human RPL7A (P62424).

DcR2 ELISA KIT|Human

EF009028 Lifescience Market 96 Tests 826.8 EUR

Anti-DcR2 antibody

PAab02271 Lifescience Market 100 ug 494.4 EUR

Recombinant Human DcR2 Protein

RP00992 Abclonal 10 μg 186 EUR

human Trail Receptor 4/DcR2/CD264

M850850048 Tecan Benelux 1 unit 279.74 EUR

Human DCR2/TNFRSF10D PicoKine ELISA Kit

EK2067 BosterBio 96 wells 510 EUR
Description: For quantitative detection of human DCR2/TNFRSF10D in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Recombinant Human DcR2 Protein, Fc & His Tag

E40KMP1006 EnoGene 20ug 495 EUR

anti-DcR2

YF-PA25185 Abfrontier 50 ul 400.8 EUR
Description: Mouse polyclonal to DcR2

human Trail Receptor 4/DcR2/CD264 1 x 96

M850850096 Tecan Benelux 1 unit 516.32 EUR

human Trail Receptor 4/DcR2/CD264 2 x 96

M850850192 Tecan Benelux 1 unit 828.95 EUR

DcR3 Antibody

24071-100ul SAB 100ul 468 EUR

DcR1 Antibody

24079-100ul SAB 100ul 468 EUR

DcR1 Antibody

24113-100ul SAB 100ul 468 EUR

DcR3 Antibody

2140-002mg ProSci 0.02 mg 206.18 EUR
Description: DcR3 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

DcR3 Antibody

2140-01mg ProSci 0.1 mg 523.7 EUR
Description: DcR3 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

DcR1 Antibody

2179-002mg ProSci 0.02 mg 206.18 EUR
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

DcR1 Antibody

2179-01mg ProSci 0.1 mg 523.7 EUR
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

DcR1 Antibody

2299-002mg ProSci 0.02 mg 206.18 EUR
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

DcR1 Antibody

2299-01mg ProSci 0.1 mg 523.7 EUR
Description: DcR1 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts are expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

DCR3 Antibody

E38PA6111 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

DcR3 Antibody

E300315 EnoGene 100ug 275 EUR
Description: Available in various conjugation types.

Dcr-1 Antibody

abx031117-400ul Abbexa 400 ul 627.6 EUR

Dcr-1 Antibody

abx031117-80l Abbexa 80 µl 343.2 EUR

Human DcR1 Antibody

33476-05111 AssayPro 150 ug 313.2 EUR

DcR3 Antibody / TNFRSF6B

F54535-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR
Description: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.

DcR3 Antibody / TNFRSF6B

F54535-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.

Polyclonal DcR3 Antibody

APR06250G Leading Biology 0.1 mg 790.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human DcR3 . This antibody is tested and proven to work in the following applications:

Polyclonal DcR1 Antibody

APR06257G Leading Biology 0.1 mg 790.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human DcR1 . This antibody is tested and proven to work in the following applications:

Polyclonal DcR1 Antibody

APR06270G Leading Biology 0.1 mg 790.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human DcR1 . This antibody is tested and proven to work in the following applications:

Human Decoy Receptor 3 (DcR3) Antibody

32129-05111 AssayPro 150 ug 313.2 EUR

Human DcR1 Antibody (Biotin Conjugate)

33476-05121 AssayPro 150 ug 442.8 EUR

DcR1 Polyclonal Antibody

41854-100ul SAB 100ul 302.4 EUR

DcR1 Polyclonal Antibody

41854-50ul SAB 50ul 224.4 EUR

DcR3 Polyclonal Antibody

ABP51153-003ml Abbkine 0.03ml 189.6 EUR
Description: A polyclonal antibody for detection of DcR3 from Human. This DcR3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human DcR3 at AA range: 220-300

DcR3 Polyclonal Antibody

ABP51153-01ml Abbkine 0.1ml 346.8 EUR
Description: A polyclonal antibody for detection of DcR3 from Human. This DcR3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human DcR3 at AA range: 220-300

DcR3 Polyclonal Antibody

ABP51153-02ml Abbkine 0.2ml 496.8 EUR
Description: A polyclonal antibody for detection of DcR3 from Human. This DcR3 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human DcR3 at AA range: 220-300

DcR1 Polyclonal Antibody

ABP53214-003ml Abbkine 0.03ml 189.6 EUR
Description: A polyclonal antibody for detection of DcR1 from Human. This DcR1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DcR1

DcR1 Polyclonal Antibody

ABP53214-01ml Abbkine 0.1ml 346.8 EUR
Description: A polyclonal antibody for detection of DcR1 from Human. This DcR1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DcR1

DcR1 Polyclonal Antibody

ABP53214-02ml Abbkine 0.2ml 496.8 EUR
Description: A polyclonal antibody for detection of DcR1 from Human. This DcR1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DcR1

DcR1 Polyclonal Antibody

ES4213-100ul ELK Biotech 100ul 334.8 EUR
Description: A Rabbit Polyclonal antibody against DcR1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

DcR1 Polyclonal Antibody

ES4213-50ul ELK Biotech 50ul 248.4 EUR
Description: A Rabbit Polyclonal antibody against DcR1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

DcR3 Polyclonal Antibody

ES2152-100ul ELK Biotech 100ul 334.8 EUR
Description: A Rabbit Polyclonal antibody against DcR3 from Human. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

DcR3 Polyclonal Antibody

ES2152-50ul ELK Biotech 50ul 248.4 EUR
Description: A Rabbit Polyclonal antibody against DcR3 from Human. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

DcR1 Polyclonal Antibody

E041854 EnoGene 100μg/100μl 255 EUR
Description: Available in various conjugation types.

DcR1 Polyclonal Antibody

E20-75483 EnoGene 100ug 225 EUR
Description: Available in various conjugation types.

DcR3 Polyclonal Antibody

E20-71303 EnoGene 100ug 225 EUR
Description: Available in various conjugation types.

Human Decoy Receptor 3 (DcR3) Antibody (Biotin Conjugate)

32129-05121 AssayPro 150 ug 442.8 EUR

DcR1 Polyclonal Conjugated Antibody

C41854 SAB 100ul 476.4 EUR

Human DcR1 AssayLite Antibody (RPE Conjugate)

33476-05151 AssayPro 150 ug 513.6 EUR

Human DcR1 AssayLite Antibody (APC Conjugate)

33476-05161 AssayPro 150 ug 513.6 EUR

Human DcR1 AssayLite Antibody (FITC Conjugate)

33476-05141 AssayPro 150 ug 513.6 EUR

Human DcR1 AssayLite Antibody (PerCP Conjugate)

33476-05171 AssayPro 150 ug 565.2 EUR

Human Decoy Receptor 3 (DcR3) AssayLite Antibody (RPE Conjugate)

32129-05151 AssayPro 150 ug 513.6 EUR

Human Decoy Receptor 3 (DcR3) AssayLite Antibody (APC Conjugate)

32129-05161 AssayPro 150 ug 513.6 EUR

Human Decoy Receptor 3 (DcR3) AssayLite Antibody (FITC Conjugate)

32129-05141 AssayPro 150 ug 513.6 EUR

Human Decoy Receptor 3 (DcR3) AssayLite Antibody (PerCP Conjugate)

32129-05171 AssayPro 150 ug 565.2 EUR

PE anti-human CD263 (DcR1, TRAIL-R3)

E16FHP263-025 EnoGene 25 tests 498.33 EUR
Description: Available in various conjugation types.

PE anti-human CD263 (DcR1, TRAIL-R3)

E16FHP263-100 EnoGene 100 tests 1083.33 EUR
Description: Available in various conjugation types.

Rabbit Anti-Drosophila Cryptochrome (dCRY) antiserum # 1

CRYD13-S Alpha Diagnostics 100 ul 548.4 EUR

Rabbit Anti-Drosophila Cryptochrome (dCRY) IgG # 1, aff pure

CRYD13-A Alpha Diagnostics 100 ug 578.4 EUR

Human Dcr1 homolog Drosophila DCR1(DICER1) ELISA Kit

YLA3763HU-48T Shanghai YL Biotech 48T 435 EUR

Human Dcr1 homolog Drosophila DCR1(DICER1) ELISA Kit

YLA3763HU-96T Shanghai YL Biotech 96T 562.5 EUR

DcR3 Peptide

2140P ProSci 0.05 mg 197.7 EUR
Description: (NT) DcR3 peptide

DcR1 Peptide

2179P ProSci 0.05 mg 197.7 EUR
Description: (ED) DcR1 peptide

DcR1 Peptide

2299P ProSci 0.05 mg 197.7 EUR
Description: (ED2) DcR1 peptide

DcR1 Rabbit pAb

E2252300 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

DcR1 / CD263 Rabbit mAb

A23554 Abclonal 100μL 83.2 EUR
Description: A synthetic peptide corresponding to a sequence within amino acids 158-257 of human MRPS15 (P82914).

Nori® Human DcR3 ELISA Kit

GR106267 Genorise Scientific 96-well 461 EUR

Dcr-1 (Center) Rabbit pAb

E2614347 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

Anti-Anti-SEPT5 Antibody antibody

STJ114819 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-SEPT7 Antibody antibody

STJ28963 St John's Laboratory 100 µl 332.4 EUR
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT3 Antibody antibody

STJ118990 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-SEPT1 antibody antibody

STJ119580 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT6 antibody antibody

STJ11100949 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT4 Antibody antibody

STJ112276 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-SEPT7 Antibody antibody

STJ116214 St John's Laboratory 100 µl 332.4 EUR
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ25475 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-SEPT5 Antibody antibody

STJ25477 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 St John's Laboratory 100 µl 332.4 EUR
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-SEPT11 Antibody antibody

STJ113941 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-SEPT11 Antibody antibody

STJ114081 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-MARCH8 Antibody antibody

STJ114828 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-SEPT12 Antibody antibody

STJ117759 St John's Laboratory 100 µl 332.4 EUR
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-MARCH6 Antibody antibody

STJ118550 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-MARCH7 Antibody antibody

STJ118752 St John's Laboratory 100 µl 332.4 EUR

Anti-Anti-SEPT11 Antibody antibody

STJ111530 St John's Laboratory 100 µl 332.4 EUR

Nori® Human DcR3 ELISA Kit (2 plates)

GR106267-2 Genorise Scientific 2 x 96-well 832 EUR

DcR3 Recombinant Protein

90-454 ProSci 100 ug 682.8 EUR
Description: Decoy receptor 3 (DcR3; TNFRSF6B; M68) is a member of the TNF receptor superfamily. DcR3 shares sequence identity with OPG (31%), TNF-RII (29%) and Fas (17%) and is expressed in a variety of different tissues and at high levels in many malignant tumors. Ligands of DcR3 include Fas ligand, homologous to lymphotoxin showing inducible expression and competing with HSV glycoprotein D for herpes virus entry mediator (a receptor expressed by T lymphocytes), TNF-like molecule 1A and heparan sulfate proteoglycans. DcR3 modulates the function of T cells, dendritic cells and macrophages. DcR3/Fc fusion proteins can bind to human and mouse B cells and suppress the activation of B cells.

ELISA kit for Human DCR3/TNFRSF6B

EK5315 SAB 96 tests 663.6 EUR
Description: Enzyme-linked immunosorbent assay kit for quantification of Human DCR3/TNFRSF6B in samples from serum, plasma, tissue homogenates and other biological fluids.

Human DcR3 / TNFRSF6B Protein, Fc Tag

TNB-H5255 ACROBIOSYSTEMS 50ug 2974.6 EUR
Description: Human DcR3, Fc Tag (TNB-H5255) is expressed from human 293 cells (HEK293). It contains AA Val 30 - His 300 (Accession # O95407-1).

human Trail Receptor 3/DcR1/CD263

M850840048 Tecan Benelux 1 unit 279.74 EUR

human Trail Receptor 3/DcR1/CD263 1 x 96

M850840096 Tecan Benelux 1 unit 516.32 EUR

human Trail Receptor 3/DcR1/CD263 2 x 96

M850840192 Tecan Benelux 1 unit 828.95 EUR

Human decoy receptor 3,DcR3 ELISA Kit

YLA4114HU-48T Shanghai YL Biotech 48T 435 EUR

Human decoy receptor 3,DcR3 ELISA Kit

YLA4114HU-96T Shanghai YL Biotech 96T 562.5 EUR

Human DcR3(Decoy receptor 3) ELISA Kit

ELK9819-48T ELK Biotech 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DcR3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DcR3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human DcR3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human DcR3 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human DcR3(Decoy receptor 3) ELISA Kit

ELK9819-96T ELK Biotech 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DcR3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DcR3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human DcR3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human DcR3 in the samples is then determined by comparing the OD of the samples to the standard curve.

Recombinant DcR3 Protein (Val 30-His 300) [Fc]

VAng-1447Lsx-1mg Creative Biolabs 1 mg 8308.8 EUR
Description: Human DcR3 (TNFRSF6B), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH17065)

Recombinant DcR3 Protein (Val 30-His 300) [Fc]

VAng-1447Lsx-50g Creative Biolabs 50 µg 1099.2 EUR
Description: Human DcR3 (TNFRSF6B), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH17065)

Human DCR3/TNFRSF6B PicoKine ELISA Kit

EK0748 BosterBio 96 wells 510 EUR
Description: For quantitative detection of human DCR3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

DcR3 / TNFRSF6B Recombinant Protein

11-549 ProSci 0.05 mg 682.8 EUR
Description: Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.

Anti-Anti-DDB1 Antibody

A00333 BosterBio 100uL 546 EUR
Description: Rabbit Polyclonal DDB1 Antibody. Validated in IP and tested in Human, Mouse.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate 6777.36 EUR
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x48wellstestplate Cloud-Clone 1x48-wells test plate 663.31 EUR
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-1x96wellstestplate Cloud-Clone 1x96-wells test plate 896.16 EUR
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

AEA465Hu-5x96wellstestplate Cloud-Clone 5x96-wells test plate 3672.72 EUR
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids.

Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit

4-AEA465Hu Cloud-Clone
  • 6837.60 EUR
  • 3613.20 EUR
  • 896.40 EUR
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Anti-AsAb(Anti-Anti-Sperm Antibody Antibody) ELISA Kit

ELK8071-48T ELK Biotech 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human Anti-AsAb protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Anti-AsAb. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Anti-AsAb in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Anti-AsAb(Anti-Anti-Sperm Antibody Antibody) ELISA Kit

ELK8071-96T ELK Biotech 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human Anti-AsAb protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Anti-AsAb. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Anti-AsAb in the samples is then determined by comparing the OD of the samples to the standard curve.

Anti-BOD1 antibody

STJ72155 St John's Laboratory 100 µg 430.8 EUR

Human DcR3 Recombinant Protein Fc Tag Lyophilized

IHUDCR3RFCLY100UG Innovative research each 802 EUR
Description: Human DcR3 Recombinant Protein Fc Tag Lyophilized

Anti-BOD1L antibody

STJ73530 St John's Laboratory 100 µg 312 EUR

anti- Antibody^Polyclonal antibody control antibody

LSMab09882 Lifescience Market 100 ug 525.6 EUR

ELISA kit for Human Anti-AsAb (Anti-Anti-Sperm Antibody Antibody)

ELK8071 ELK Biotech 1 plate of 96 wells 518.4 EUR
Description: A competitive Inhibition ELISA kit for detection of Anti-Anti-Sperm Antibody Antibody from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-2B4 Antibody

HA500180 HUABIO 100ul 189 EUR
Description: This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-2B4 Antibody

HA500263 HUABIO 100ul 189 EUR
Description: Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor . Activating function implicates association with SH2D1A and FYN . Downstreaming signaling involves predominantly VAV1, and, to a lesser degree, INPP5D/SHIP1 and CBL. Signal attenuation in the absence of SH2D1A is proposed to be dependent on INPP5D and to a lesser extent PTPN6/SHP-1 and PTPN11/SHP-2. Stimulates NK cell cytotoxicity, production of IFN-gamma and granule exocytosis . Optimal expansion and activation of NK cells seems to be dependent on the engagement of CD244 with CD48 expressed on neighboring NK cells. Acts as costimulator in NK activation by enhancing signals by other NK receptors such as NCR3 and NCR1. At early stages of NK cell differentiation may function as an inhibitory receptor possibly ensuring the self-tolerance of developing NK cells. Involved in the regulation of CD8+ T-cell proliferation; expression on activated T-cells and binding to CD488 provides costimulatory-like function for neighboring T-cells. Inhibits inflammatory responses in dendritic cells (DCs) .

Anti-7B2 antibody

STJ191062 St John's Laboratory 200 µl 236.4 EUR
Description: Unconjugated Rabbit polyclonal to 7B2

Anti-4.1G Antibody

A03718 BosterBio 100ul 476.4 EUR
Description: Rabbit Polyclonal Antibody for 4.1G Antibody (EPB41L2) detection.tested for WB in Human.

Anti-4.1G antibody

STJ91381 St John's Laboratory 200 µl 236.4 EUR
Description: Rabbit polyclonal to 4.1G.

Anti-4.1R antibody

STJ91382 St John's Laboratory 200 µl 236.4 EUR
Description: Rabbit polyclonal to 4.1R.

Anti-BOC Antibody

PA1904 BosterBio 100ug/vial 352.8 EUR

Anti-BOK antibody

STJ190601 St John's Laboratory 200 µl 236.4 EUR
Description: Unconjugated Rabbit polyclonal to BOK

Anti-BOC antibody

STJ71520 St John's Laboratory 100 µg 430.8 EUR

Anti-BOK antibody

STJ72368 St John's Laboratory 100 µg 430.8 EUR

Anti-BOC antibody

STJ192335 St John's Laboratory 200 µl 236.4 EUR
Description: Unconjugated Rabbit polyclonal to BOC

Anti-BOC antibody

STJ29254 St John's Laboratory 100 µl 332.4 EUR
Description: The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Anti-BoV antibody

STJ400075 St John's Laboratory 1 mg 535.2 EUR
Description: Human bocavirus (also termed HBoV) is a small non-enveloped virus with a single- stranded DNA genome. It is a member of the Parvoviridae family. HBoV has been detected worldwide in 2–20 % of all upper and lower respiratory tract infections, and has also been linked to gastroenteritis.
In this Review, we talk about the proof supporting the strikingly distinct allele-dependent scientific phenotypes noticed in carriers of such gene mutations and its affect on the wider area of neurodegeneration.
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