Neurodevelopmental issues (NDDs) are a heterogeneous and extremely prevalent group of psychiatric situations marked by impairments in the nervous system. Their onset happens throughout gestation, and the alterations are noticed all through the postnatal life. Although many genetic and environmental danger elements have been described in this context, the interactions between them problem the understanding of the pathways related to NDDs.
Transcription elements (TFs) – a bunch of over 1,600 proteins that may work together with DNA, regulating gene expression by modulation of RNA synthesis, signify some extent of convergence for completely different danger elements. In addition, TFs manage vital processes like angiogenesis, blood-brain barrier formation, myelination, neuronal migration, immune activation, and many others in a time and location-dependent means.
In this assessment, we summarize essential TF alterations in NDD and related issues, together with particular impairments noticed in animal fashions, and, lastly, set up hypotheses to elucidate how these proteins could also be vital mediators in the context of genome-environment interactions.
Reappraisal of metabolic dysfunction in neurodegeneration: Focus on mitochondrial operate and calcium signaling
The mobile and molecular mechanisms that drive neurodegeneration stay poorly outlined. Recent scientific trial failures, tough prognosis, unsure etiology, and lack of healing therapies prompted us to re-examine different hypotheses of neurodegenerative pathogenesis. Recent studies set up that mitochondrial and calcium dysregulation happen early in many neurodegenerative ailments (NDDs), together with Alzheimer’s illness, Parkinson’s illness, Huntington’s illness, and others.
However, causal molecular proof of mitochondrial and metabolic contributions to pathogenesis stays inadequate. Here we summarize the information supporting the speculation that mitochondrial and metabolic dysfunction outcome from numerous etiologies of neuropathology.
We present a present and complete assessment of the literature and interpret that faulty mitochondrial metabolism is upstream and major to protein aggregation and different dogmatic hypotheses of NDDs. Finally, we determine gaps in data and suggest therapeutic modulation of mCa2+ change and mitochondrial operate to alleviate metabolic impairments and deal with NDDs.
Protein phosphatase 2A – construction, operate and position in neurodevelopmental issues
Neurodevelopmental issues (NDDs), together with mental incapacity (ID), autism and schizophrenia, have excessive socioeconomic affect, but poorly understood etiologies. A current surge of large-scale genome or exome sequencing research has recognized a mess of largely de novo mutations in subunits of the protein phosphatase 2A (PP2A) holoenzyme which are strongly related to NDDs.
PP2A is accountable for at the least 50% of complete Ser/Thr dephosphorylation in most cell varieties and is predominantly discovered as trimeric holoenzymes composed of catalytic (C), scaffolding (A) and variable regulatory (B) subunits. PP2A can exist in practically 100 completely different subunit combos in mammalian cells, dictating distinct localizations, substrates and regulatory mechanisms.
PP2A is properly established as a regulator of cell division, progress, and differentiation, and the roles of PP2A in most cancers and numerous neurodegenerative issues, similar to Alzheimer’s illness, have been reviewed in element. This Review summarizes and discusses current studies on NDDs related to mutations of PP2A subunits and PP2A-associated proteins. We additionally focus on the potential affect of those mutations on the construction and operate of the PP2A holoenzymes and the etiology of NDDs.
Muscarinic Acetylcholine Receptor M1 mutations inflicting neurodevelopmental dysfunction and epilepsy
De novo uncommon damaging variants in genes concerned in vital developmental pathways, notably regulation of synaptic transmission, have emerged as a frequent explanation for neurodevelopmental issues (NDD). NDD present nice locus heterogeneity and for most of the related genes there’s substantial phenotypic variety, together with epilepsy, mental incapacity, autism spectrum dysfunction, motion issues and combos thereof.
We report two unrelated sufferers, a younger lady with early-onset refractory epilepsy, extreme incapacity and progressive cerebral and cerebellar atrophy and a second lady with delicate dysmorphism, world developmental delay and average mental incapacity in whom trio-based complete exome sequencing evaluation uncovered de novo missense variants in CHRM1.
Biochemical analyses of one of many NDD-associated variants proved that it brought on a discount in protein ranges and an impaired mobile trafficking. In addition, the mutated receptor confirmed faulty activation of intracellular signalling pathways. Our information strengthen the idea that mind diminished muscarinic signalling lowers seizure threshold and severely impairs neurodevelopment. This article is protected by copyright. All rights reserved.
Marine Polysaccharides as a Versatile Biomass for the Construction of Nano Drug Delivery Systems
Marine biomass is a treasure trove of supplies. Marine polysaccharides have the traits of biocompatibility, biodegradability, non-toxicity, low price, and abundance. An huge number of polysaccharides might be extracted from marine organisms similar to algae, crustaceans, and microorganisms. The most studied marine polysaccharides embody chitin, chitosan, alginates, hyaluronic acid, fucoidan, carrageenan, agarose, and Ulva. Marine polysaccharides have a variety of purposes in the sphere of biomedical supplies, similar to drug supply, tissue engineering, wound dressings, and sensors.
The drug supply system (DDS) can comprehensively management the distribution of medicine in the organism in area, time, and dosage, thereby growing the utilization effectivity of medicine, lowering prices, and lowering poisonous unwanted side effects. The nano-drug supply system (NDDS), on account of its small measurement, can operate on the subcellular degree in vivo.
TNFRSF10D Antibody |
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| 1-CSB-PA887006ESR1HU | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
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TNFRSF10D Antibody |
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| 1-CSB-PA887006ESR2HU | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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TNFRSF10D Antibody |
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| 1-CSB-PA909727 | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300 |
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TNFRSF10D Antibody |
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| 1-CSB-PA070147 | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000 |
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TNFRSF10D Antibody |
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| 1-CSB-PA08209A0Rb | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
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TNFRSF10D Antibody |
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| 1-CSB-PA057438 | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
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TNFRSF10D Antibody |
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| DF4811 | Affbiotech | 200ul | 420 EUR |
TNFRSF10D siRNA |
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| 20-abx937586 | Abbexa |
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TNFRSF10D Antibody |
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| CSB-PA031451-100ul | Cusabio | 100ul | 379.2 EUR |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
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TNFRSF10D Antibody |
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| 1-CSB-PA023967GA01HU | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC |
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TNFRSF10D Antibody |
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| CSB-PA031451- | Cusabio | each | 402 EUR |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
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Human TNFRSF10D shRNA Plasmid |
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| 20-abx955793 | Abbexa |
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Human TNFRSF10D ELISA KIT |
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| ELI-36682h | Lifescience Market | 96 Tests | 988.8 EUR |
TNFRSF10D Rabbit pAb |
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| A0184-100ul | Abclonal | 100 ul | 369.6 EUR |
TNFRSF10D Rabbit pAb |
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| A0184-200ul | Abclonal | 200 ul | 550.8 EUR |
TNFRSF10D Rabbit pAb |
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| A0184-20ul | Abclonal | 20 ul | Ask for price |
TNFRSF10D Rabbit pAb |
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| A0184-50ul | Abclonal | 50 ul | Ask for price |
TNFRSF10D Rabbit pAb |
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| A14078-100ul | Abclonal | 100 ul | 369.6 EUR |
TNFRSF10D Rabbit pAb |
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| A14078-200ul | Abclonal | 200 ul | 550.8 EUR |
TNFRSF10D Rabbit pAb |
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| A14078-20ul | Abclonal | 20 ul | 219.6 EUR |
TNFRSF10D Rabbit pAb |
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| A14078-50ul | Abclonal | 50 ul | 267.6 EUR |
TNFRSF10D Rabbit pAb |
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| A6136-100ul | Abclonal | 100 ul | 369.6 EUR |
TNFRSF10D Rabbit pAb |
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| A6136-200ul | Abclonal | 200 ul | 550.8 EUR |
TNFRSF10D Rabbit pAb |
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| A6136-20ul | Abclonal | 20 ul | 219.6 EUR |
TNFRSF10D Rabbit pAb |
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| A6136-50ul | Abclonal | 50 ul | 267.6 EUR |
TNFRSF10D cloning plasmid |
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| CSB-CL887006HU-10ug | Cusabio | 10ug | 279.6 EUR |
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Description: A cloning plasmid for the TNFRSF10D gene. |
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TNFRSF10D Blocking Peptide |
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| DF4811-BP | Affbiotech | 1mg | 234 EUR |
TNFRSF10D Conjugated Antibody |
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| C35312 | SAB | 100ul | 476.4 EUR |
TNFRSF10D Polyclonal Antibody |
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| A71327-050 | EpiGentek | 50 ul | 302.5 EUR |
TNFRSF10D Polyclonal Antibody |
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| A71327-100 | EpiGentek | 100 ul | 423.5 EUR |
TNFRSF10D Polyclonal Antibody |
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| A71328-050 | EpiGentek | 50 ul | 302.5 EUR |
TNFRSF10D Polyclonal Antibody |
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| A71328-100 | EpiGentek | 100 ul | 423.5 EUR |
TNFRSF10D Polyclonal Antibody |
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| A54081-020 | EpiGentek | 20 ul | 117.7 EUR |
TNFRSF10D Polyclonal Antibody |
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| A54081-050 | EpiGentek | 50 ul | 302.5 EUR |
TNFRSF10D Polyclonal Antibody |
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| A54081-100 | EpiGentek | 100 ul | 423.5 EUR |
TNFRSF10D Polyclonal Antibody |
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| A54081 | EpiGentek |
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TNFRSF10D Polyclonal Antibody |
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| A71327 | EpiGentek |
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TNFRSF10D Polyclonal Antibody |
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| A71328 | EpiGentek |
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TNFRSF10D ELISA Kit (Human) (OKBB01434) |
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| OKBB01434 | Aviva Systems Biology | 96 Wells | 606 EUR |
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Description: Description of target: Decoy receptor 2 (DCR2), also known as TRAIL receptor 4 (TRAILR4) and tumor necrosis factor receptor superfamily member 10D (TNFRSF10D), is a human cell surface receptor of the TNF-receptor superfamily. It is mapped to 8p21.3. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplasmic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml |
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TNFRSF10D ELISA Kit (Human) (OKEH04990) |
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| OKEH04990 | Aviva Systems Biology | 96 Wells | 715.2 EUR |
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Description: Description of target: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL |
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TNFRSF10D ORF Vector (Human) (pORF) |
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| ORF010806 | ABM | 1.0 ug DNA | 114 EUR |
TNFRSF10D ELISA Kit (Human) (OKCA02319) |
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| OKCA02319 | Aviva Systems Biology | 96 Wells | 913.2 EUR |
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Description: Description of target: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: 0.078 ng/mL |
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Polyclonal Goat anti-GST α-form |
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| GST-ANTI-1 | Detroit R&D | 50 uL | 336 EUR |
Polyclonal Goat anti-GST μ-form |
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| GST-ANTI-2 | Detroit R&D | 50 uL | 336 EUR |
Polyclonal Goat anti-GST p-form |
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| GST-ANTI-3 | Detroit R&D | 50 uL | 336 EUR |
Polyclonal TNFRSF10D Antibody (Center) |
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| APR06175G | Leading Biology | 0.1ml | 580.8 EUR |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TNFRSF10D (Center). This antibody is tested and proven to work in the following applications: |
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TNFRSF10D Antibody, HRP conjugated |
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| 1-CSB-PA08209B0Rb | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
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TNFRSF10D Antibody, FITC conjugated |
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| 1-CSB-PA08209C0Rb | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
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TNFRSF10D Antibody, Biotin conjugated |
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| 1-CSB-PA08209D0Rb | Cusabio |
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Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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Human DCR2/TNFRSF10D PicoKine ELISA Kit |
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| EK2067 | BosterBio | 96 wells | 510 EUR |
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Description: For quantitative detection of human DCR2/TNFRSF10D in cell culture supernates, serum and plasma (heparin, EDTA, citrate). |
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TNFRSF10D sgRNA CRISPR Lentivector set (Human) |
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| K2415801 | ABM | 3 x 1.0 ug | 406.8 EUR |
Human CellExp? TNFRSF10D / TRAIL R4, human recombinant |
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| P1140-10 | Biovision | each | 157.2 EUR |
Human CellExp? TNFRSF10D / TRAIL R4, human recombinant |
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| P1140-50 | Biovision | each | 470.4 EUR |
Polyclonal TNFRSF10D Antibody (C-term) |
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| APR03859G | Leading Biology | 0.1ml | 580.8 EUR |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TNFRSF10D (C-term). This antibody is tested and proven to work in the following applications: |
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TNFRSF10D Polyclonal Antibody, HRP Conjugated |
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| A54082-050 | EpiGentek | 50 ul | 302.5 EUR |
TNFRSF10D Polyclonal Antibody, HRP Conjugated |
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| A54082-100 | EpiGentek | 100 ul | 423.5 EUR |
TNFRSF10D Polyclonal Antibody, FITC Conjugated |
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| A54083-050 | EpiGentek | 50 ul | 302.5 EUR |
TNFRSF10D Polyclonal Antibody, FITC Conjugated |
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| A54083-100 | EpiGentek | 100 ul | 423.5 EUR |
TNFRSF10D Polyclonal Antibody, Biotin Conjugated |
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| A54084-050 | EpiGentek | 50 ul | 302.5 EUR |
TNFRSF10D Polyclonal Antibody, Biotin Conjugated |
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| A54084-100 | EpiGentek | 100 ul | 423.5 EUR |
TNFRSF10D Polyclonal Antibody, HRP Conjugated |
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| A54082 | EpiGentek |
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TNFRSF10D Polyclonal Antibody, FITC Conjugated |
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| A54083 | EpiGentek |
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TNFRSF10D Polyclonal Antibody, Biotin Conjugated |
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| A54084 | EpiGentek |
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TNFRSF10D sgRNA CRISPR Lentivector (Human) (Target 1) |
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| K2415802 | ABM | 1.0 ug DNA | 184.8 EUR |
TNFRSF10D sgRNA CRISPR Lentivector (Human) (Target 2) |
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| K2415803 | ABM | 1.0 ug DNA | 184.8 EUR |
TNFRSF10D sgRNA CRISPR Lentivector (Human) (Target 3) |
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| K2415804 | ABM | 1.0 ug DNA | 184.8 EUR |
TNFRSF10D Protein Vector (Human) (pPB-C-His) |
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| PV043221 | ABM | 500 ng | 394.8 EUR |
TNFRSF10D Protein Vector (Human) (pPB-N-His) |
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| PV043222 | ABM | 500 ng | 394.8 EUR |
TNFRSF10D Protein Vector (Human) (pPM-C-HA) |
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| PV043223 | ABM | 500 ng | 394.8 EUR |
TNFRSF10D Protein Vector (Human) (pPM-C-His) |
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| PV043224 | ABM | 500 ng | 394.8 EUR |
Recombinant Human TNFRSF10D Protein, His, Insect-1ug |
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| QP10888-1ug | EnQuireBio | 1ug | 186 EUR |
Recombinant Human TNFRSF10D Protein, His, Insect-50ug |
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| QP10888-50ug | EnQuireBio | 50ug | 1513.2 EUR |
Recombinant Human TNFRSF10D Protein, His, Insect-5ug |
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| QP10888-5ug | EnQuireBio | 5ug | 241.2 EUR |
Recombinant Human TRAIL R4/TNFRSF10D/CD264 (C-Fc) |
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| CU11-10ug | Novoprotein | 10ug | 145.2 EUR |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Human TRAIL R4/TNFRSF10D/CD264 (C-Fc) |
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| CU11-1mg | Novoprotein | 1mg | 1216.8 EUR |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Human TRAIL R4/TNFRSF10D/CD264 (C-Fc) |
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| CU11-500ug | Novoprotein | 500ug | 868.8 EUR |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Recombinant Human TRAIL R4/TNFRSF10D/CD264 (C-Fc) |
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| CU11-50ug | Novoprotein | 50ug | 242.4 EUR |
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Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
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Human CellExp? TNFRSF10D / TRAIL R4, Fc Tag, Human recombinant |
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| P1139-20 | Biovision | each | 157.2 EUR |
Human CellExp? TNFRSF10D / TRAIL R4, Fc Tag, Human recombinant |
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| P1139-50 | Biovision | each | 301.2 EUR |
TNFRSF10D 3'UTR GFP Stable Cell Line |
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| TU076019 | ABM | 1.0 ml | 1825.2 EUR |
TNFRSF10D 3'UTR Luciferase Stable Cell Line |
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| TU026019 | ABM | 1.0 ml | 1825.2 EUR |
TNFRSF10D sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
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| K2415805 | ABM | 3 x 1.0 ug | 451.2 EUR |
Human Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) ELISA Kit |
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| abx521076-96tests | Abbexa | 96 tests | 801.6 EUR |
Human TNFRSF10D/ Tumor necrosis factor receptor superfamily member 10D ELISA Kit |
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| E2533Hu | Sunlong | 1 Kit | 675.6 EUR |
TNFRSF10D sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
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| K2415806 | ABM | 1.0 ug DNA | 200.4 EUR |
TNFRSF10D sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
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| K2415807 | ABM | 1.0 ug DNA | 200.4 EUR |
TNFRSF10D sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
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| K2415808 | ABM | 1.0 ug DNA | 200.4 EUR |
Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| abx038204-100ug | Abbexa | 100 ug | 469.2 EUR |
Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| 20-abx004693 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| 20-abx000583 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| 20-abx110314 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| 20-abx015189 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| abx034407-400ul | Abbexa | 400 ul | 627.6 EUR |
Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| abx034407-80l | Abbexa | 80 µl | 343.2 EUR |
Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| abx027574-400ul | Abbexa | 400 ul | 627.6 EUR |
Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| abx027574-80l | Abbexa | 80 µl | 343.2 EUR |
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) Antibody |
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| 20-abx210250 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| 20-abx320290 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody |
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| 20-abx322150 | Abbexa |
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Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) Antibody |
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| 20-abx323347 | Abbexa |
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Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) Antibody |
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| abx331215-100ul | Abbexa | 100 ul | 510 EUR |
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) Antibody |
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| 20-abx210905 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody (HRP) |
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| 20-abx108862 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody (Biotin) |
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| 20-abx106028 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody (FITC) |
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| 20-abx107442 | Abbexa |
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Tumor Necrosis Factor Receptor Superfamily Member 10D (TNFRSF10D) Antibody Pair |
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| abx117523-1pair5x96wellplates | Abbexa | 1 pair (5x96 well plates) | 1212 EUR |
Tumor necrosis factor receptor superfamily member 10d (TNFRSF10D) polyclonal antibody |
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| ABP-PAB-10298 | Allele Biotech | 100 ug | Ask for price |
anti-human CCR1 |
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| 20R-3028 | Fitzgerald | 200 ug | 704.4 EUR |
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Description: Goat anti-human CCR1 antibody |
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anti-human RecQL4 |
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| AR05-PA0007 | Abfrontier | 100 ul | 400.8 EUR |
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Description: Rabbit polyclonal to human RecQL4 |
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Anti-Human IgG |
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| DB-173-0.1 | DB Biotech | 100 μl | 254.4 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-0.2 | DB Biotech | 200 μl | 357.6 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-0.5 | DB Biotech | 500 μl | 460.8 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-1 | DB Biotech | 1 ml | 735.6 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-173-RTU-15 | DB Biotech | 15 ml | 426 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB-173-RTU-7 | DB Biotech | 7 ml | 277.2 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB-174-0.1 | DB Biotech | 100 μl | 254.4 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-0.2 | DB Biotech | 200 μl | 357.6 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-0.5 | DB Biotech | 500 μl | 460.8 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-1 | DB Biotech | 1 ml | 735.6 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
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Anti-Human IgG |
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| DB-174-RTU-15 | DB Biotech | 15 ml | 426 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB-174-RTU-7 | DB Biotech | 7 ml | 277.2 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB173RTU-15 | DB Biotech | 15 ml | 426 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB173RTU-7 | DB Biotech | 7 ml | 277.2 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB174RTU-15 | DB Biotech | 15 ml | 426 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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Anti-Human IgG |
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| DB174RTU-7 | DB Biotech | 7 ml | 277.2 EUR |
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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anti-human Albumin |
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| LF-PA10001 | Abfrontier | 100 ug | 483.6 EUR |
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Description: Rabbit polyclonal to human Albumin |
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Goat anti-Human anti-thrombin polyclonal antibody |
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| CABT-L487 | Creative Diagnostics | 500ug | 858 EUR |
Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L488 | Creative Diagnostics | 500ug | 795.6 EUR |
Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L489 | Creative Diagnostics | 100ug | 795.6 EUR |
Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L490 | Creative Diagnostics | 100ug | 795.6 EUR |
Sheep anti-Human anti-thrombin polyclonal antibody |
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| CABT-L491 | Creative Diagnostics | 100ug | 795.6 EUR |
Human anti AMPH(anti amphiphysin) ELISA Kit |
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| EH2621 | FN Test | 96T | 628.92 EUR |
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Description: Method of detection: Sandwich ELISA, Double Antigen;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
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Human anti-TPO(anti-thrombopoietin) ELISA Kit |
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| EH4147 | FN Test | 96T | 628.92 EUR |
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Description: Method of detection: Sandwich ELISA, Double Antigen;Reacts with: Homo sapiens ;Sensitivity: 0.938 ng/ml |
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Anti-Procalcitonin antibody *Mouse anti-human, monoclonal * |
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| V100125 | AAT Bioquest | 50 ug | 367.2 EUR |
Anti-Procalcitonin antibody *Mouse anti-human, monoclonal * |
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| V100126 | AAT Bioquest | 1 mg | 471.6 EUR |
Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | 6777.36 EUR |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | 663.31 EUR |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | 896.16 EUR |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| AEA465Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | 3672.72 EUR |
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Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
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Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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| 4-AEA465Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
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Goat anti Human IgG |
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| 70C-CR6047GAP | Fitzgerald | 1 mg | 178.8 EUR |
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Description: Affinity purified Goat anti Human IgG antibody |
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Goat anti Human IgM |
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| 70-B9022GA00-A0 | Fitzgerald | 5 mg | 230.4 EUR |
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Description: Goat anti Human IgM antibody |
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Mouse anti Human IgE |
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| 10-1025 | Fitzgerald | 1 mg | 392.4 EUR |
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Description: Mouse monoclonal Mouse anti Human IgE antibody |
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Mouse anti Human IgE |
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| 10-1026 | Fitzgerald | 1 mg | 392.4 EUR |
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Description: Mouse monoclonal Mouse anti Human IgE antibody |
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Mouse anti Human IgE |
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| 10-1027 | Fitzgerald | 1 mg | 392.4 EUR |
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Description: Mouse monoclonal Mouse anti Human IgE antibody |
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Mouse anti Human IgA |
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| 10-7808 | Fitzgerald | 1 mg | 403.2 EUR |
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Description: Mouse anti Human IgA antibody |
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Mouse anti Human IgA |
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| 10-I05A | Fitzgerald | 1 mg | 369.6 EUR |
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Description: Mouse anti Human IgA antibody |
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Mouse anti Human IgE |
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| 10-I104B | Fitzgerald | 1 mg | 403.2 EUR |
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Description: Mouse anti Human IgE antibody |
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Mouse anti Human IgE |
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| 10-I104CC | Fitzgerald | 1 mg | 403.2 EUR |
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Description: Mouse anti Human IgE antibody |
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Mouse anti Human IgE |
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| 10-I10A | Fitzgerald | 1 mg | 217.2 EUR |
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Description: Mouse anti Human IgE antibody |
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Mouse anti Human IgE |
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| 10-I10C | Fitzgerald | 1 mg | 217.2 EUR |
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Description: Mouse anti Human IgE antibody |
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Mouse anti Human IgE |
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| 10-I10E | Fitzgerald | 1 mg | 594 EUR |
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Description: Mouse anti Human IgE antibody |
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Mouse anti Human IgM |
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| 10-I20A | Fitzgerald | 1 mg | 229.2 EUR |
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Description: Mouse anti Human IgM antibody |
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Mouse anti Human IgM |
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| 10-I20B | Fitzgerald | 1 mg | 354 EUR |
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Description: Mouse anti Human IgM antibody |
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Mouse anti Human IgM |
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| 10-I20G | Fitzgerald | 1 mg | 354 EUR |
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Description: Mouse anti Human IgM antibody |
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Mouse anti Human IgM |
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| 10-I20H | Fitzgerald | 1 mg | 224.4 EUR |
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Description: Mouse anti Human IgM antibody |
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Mouse anti Human IgG1 |
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| 10-I21A | Fitzgerald | 200 ug | 264 EUR |
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Description: Mouse anti Human IgG1 antibody |
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Mouse anti Human IgG2 |
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| 10-I22A | Fitzgerald | 200 ug | 470.4 EUR |
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Description: Mouse anti Human IgG2 antibody |
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Mouse anti Human IgG3 |
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| 10-I23A | Fitzgerald | 200 ug | 762 EUR |
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Description: Mouse anti Human IgG3 antibody |
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Mouse anti Human IgG4 |
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| 10-I24A | Fitzgerald | 200 ug | 470.4 EUR |
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Description: Mouse anti Human IgG4 antibody |
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Mouse anti Human IgE |
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| 10-S9601MND1-M0 | Fitzgerald | 1 mg | 262.8 EUR |
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Description: Mouse anti Human IgE antibody |
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Anti-CCR10 (human) Antibody |
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| A04731 | BosterBio | 200ug | 476.4 EUR |
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Description: Goat Polyclonal CCR10 (human) Antibody. Validated in ELISA, IF, IHC and tested in Human. |
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Anti-TRAIL (human) Antibody |
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| A00466-2 | BosterBio | 100ul | 500.4 EUR |
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Description: Rabbit Polyclonal TRAIL (human) Antibody. Validated in IF, IHC and tested in Human. |
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Anti-CCR4 (human) Antibody |
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| A00755-1 | BosterBio | 200ug | 476.4 EUR |
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Description: Goat Polyclonal CCR4 (human) Antibody. Validated in IF, IHC and tested in Human. |
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Goat anti Human IgG |
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| 41C-CB0957 | Fitzgerald | 5 mg | 415.2 EUR |
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Description: Goat anti Human IgG secondary antibody |
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Goat anti Human IgG |
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| 41C-CB0972 | Fitzgerald | 2 mg | 316.8 EUR |
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Description: Goat anti Human IgG secondary antibody |
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The marine polysaccharide-based DDS combines the benefits of polysaccharide supplies and nanotechnology, and is appropriate as a provider for completely different pharmaceutical preparations. This assessment summarizes the benefits and drawbacks of utilizing marine polysaccharides to assemble the NDDS and describes the preparation strategies and modification methods of marine polysaccharide-based nanocarriers.
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