Transcription Factors in Neurodevelopmental and Associated Psychiatric Disorders: A Potential Convergence for Genetic and Environmental Risk Factors

Transcription Factors in Neurodevelopmental and Associated Psychiatric Disorders: A Potential Convergence for Genetic and Environmental Risk Factors

Neurodevelopmental issues (NDDs) are a heterogeneous and extremely prevalent group of psychiatric situations marked by impairments in the nervous system. Their onset happens throughout gestation, and the alterations are noticed all through the postnatal life. Although many genetic and environmental danger elements have been described in this context, the interactions between them problem the understanding of the pathways related to NDDs.
Transcription elements (TFs) – a bunch of over 1,600 proteins that may work together with DNA, regulating gene expression by modulation of RNA synthesis, signify some extent of convergence for completely different danger elements. In addition, TFs manage vital processes like angiogenesis, blood-brain barrier formation, myelination, neuronal migration, immune activation, and many others in a time and location-dependent means.
In this assessment, we summarize essential TF alterations in NDD and related issues, together with particular impairments noticed in animal fashions, and, lastly, set up hypotheses to elucidate how these proteins could also be vital mediators in the context of genome-environment interactions.

Reappraisal of metabolic dysfunction in neurodegeneration: Focus on mitochondrial operate and calcium signaling

The mobile and molecular mechanisms that drive neurodegeneration stay poorly outlined. Recent scientific trial failures, tough prognosis, unsure etiology, and lack of healing therapies prompted us to re-examine different hypotheses of neurodegenerative pathogenesis. Recent studies set up that mitochondrial and calcium dysregulation happen early in many neurodegenerative ailments (NDDs), together with Alzheimer’s illness, Parkinson’s illness, Huntington’s illness, and others.
However, causal molecular proof of mitochondrial and metabolic contributions to pathogenesis stays inadequate. Here we summarize the information supporting the speculation that mitochondrial and metabolic dysfunction outcome from numerous etiologies of neuropathology.
We present a present and complete assessment of the literature and interpret that faulty mitochondrial metabolism is upstream and major to protein aggregation and different dogmatic hypotheses of NDDs. Finally, we determine gaps in data and suggest therapeutic modulation of mCa2+ change and mitochondrial operate to alleviate metabolic impairments and deal with NDDs.

Protein phosphatase 2A – construction, operate and position in neurodevelopmental issues

Neurodevelopmental issues (NDDs), together with mental incapacity (ID), autism and schizophrenia, have excessive socioeconomic affect, but poorly understood etiologies. A current surge of large-scale genome or exome sequencing research has recognized a mess of largely de novo mutations in subunits of the protein phosphatase 2A (PP2A) holoenzyme which are strongly related to NDDs.
Transcription Factors in Neurodevelopmental and Associated Psychiatric Disorders: A Potential Convergence for Genetic and Environmental Risk Factors
PP2A is accountable for at the least 50% of complete Ser/Thr dephosphorylation in most cell varieties and is predominantly discovered as trimeric holoenzymes composed of catalytic (C), scaffolding (A) and variable regulatory (B) subunits. PP2A can exist in practically 100 completely different subunit combos in mammalian cells, dictating distinct localizations, substrates and regulatory mechanisms.
PP2A is properly established as a regulator of cell division, progress, and differentiation, and the roles of PP2A in most cancers and numerous neurodegenerative issues, similar to Alzheimer’s illness, have been reviewed in element. This Review summarizes and discusses current studies on NDDs related to mutations of PP2A subunits and PP2A-associated proteins. We additionally focus on the potential affect of those mutations on the construction and operate of the PP2A holoenzymes and the etiology of NDDs.

Muscarinic Acetylcholine Receptor M1 mutations inflicting neurodevelopmental dysfunction and epilepsy

De novo uncommon damaging variants in genes concerned in vital developmental pathways, notably regulation of synaptic transmission, have emerged as a frequent explanation for neurodevelopmental issues (NDD). NDD present nice locus heterogeneity and for most of the related genes there’s substantial phenotypic variety, together with epilepsy, mental incapacity, autism spectrum dysfunction, motion issues and combos thereof.
We report two unrelated sufferers, a younger lady with early-onset refractory epilepsy, extreme incapacity and progressive cerebral and cerebellar atrophy and a second lady with delicate dysmorphism, world developmental delay and average mental incapacity in whom trio-based complete exome sequencing evaluation uncovered de novo missense variants in CHRM1.
Biochemical analyses of one of many NDD-associated variants proved that it brought on a discount in protein ranges and an impaired mobile trafficking. In addition, the mutated receptor confirmed faulty activation of intracellular signalling pathways. Our information strengthen the idea that mind diminished muscarinic signalling lowers seizure threshold and severely impairs neurodevelopment. This article is protected by copyright. All rights reserved.

Marine Polysaccharides as a Versatile Biomass for the Construction of Nano Drug Delivery Systems

Marine biomass is a treasure trove of supplies. Marine polysaccharides have the traits of biocompatibility, biodegradability, non-toxicity, low price, and abundance. An huge number of polysaccharides might be extracted from marine organisms similar to algae, crustaceans, and microorganisms. The most studied marine polysaccharides embody chitin, chitosan, alginates, hyaluronic acid, fucoidan, carrageenan, agarose, and Ulva. Marine polysaccharides have a variety of purposes in the sphere of biomedical supplies, similar to drug supply, tissue engineering, wound dressings, and sensors.
The drug supply system (DDS) can comprehensively management the distribution of medicine in the organism in area, time, and dosage, thereby growing the utilization effectivity of medicine, lowering prices, and lowering poisonous unwanted side effects. The nano-drug supply system (NDDS), on account of its small measurement, can operate on the subcellular degree in vivo.

Rabbit anti Human TNFRSF10D  Monoclonal Antibody

MBS2543981-02mL MyBiosource 0.2mL 550 EUR

Human TNFRSF10D siRNA

20-abx937586 Abbexa
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  • 15 nmol
  • 30 nmol

Anti-Human TNFRSF10D Antibody

101-M654 ReliaTech 100 µg 399 EUR
Description: TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. TRAIL binds at least five different receptors: TRAIL R1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (OPG). TRAIL receptors all exhibit cysteine-rich repeats characteristic of the TNF receptor superfamily. TRAIL R1 and R2 are type 1 transmembrane proteins with intracellular death domains (DD) and, subsequently, have the ability to mediate TRAIL-induced apoptosis. The remaining receptors are decoys that may regulate TRAIL activity by competing for binding sites with TRAIL R1 and R2. TRAIL R3 is membrane-associated via GPI linkage. TRAIL R4 is a type 1 transmembrane receptor, but exhibits a truncated cytoplasmic domain. Like the active receptors TRAIL R1 and R2, OPG has a DD motif but is a soluble protein.

TNFRSF10D siRNA (Human)

MBS8232418-15nmol MyBiosource 15nmol 405 EUR

TNFRSF10D siRNA (Human)

MBS8232418-30nmol MyBiosource 30nmol 565 EUR

TNFRSF10D siRNA (Human)

MBS8232418-5x30nmol MyBiosource 5x30nmol 2450 EUR

Human TNFRSF10D ELISA KIT

ELI-36682h Lifescience Market 96 Tests 988.8 EUR

Human TNFRSF10D shRNA Plasmid

20-abx955793 Abbexa
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  • 150 µg
  • 300 µg

Human TNFRSF10D Protein Lysate

MBS8428897-INQUIRE MyBiosource INQUIRE Ask for price

Recombinant Human TNFRSF10D Protein

E30P01243A EnoGene 50 ug 295 EUR

Anti-DcR2 TNFRSF10D Antibody

A05136-1 BosterBio 0.1mg 449 EUR
Description: Boster Bio Anti-DcR2 TNFRSF10D Antibody (Catalog # A05136-1). Tested in ELISA, WB, ICC, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Human TNFRSF10D Protein, Fc Tag

E40KMPH6289 EnoGene 20ug 495 EUR

Human TNFRSF10D Protein, His Tag

E40KMPH1573 EnoGene 20ug 495 EUR

Human TNFRSF10D knockout cell line

ABC-KH15834 AcceGen 1 vial Ask for price
Description: Human TNFRSF10D knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

TNFRSF10D ORF Vector (Human) (pORF)

ORF010806 ABM 1.0 ug DNA 114 EUR

Human TNFRSF10D knockdown cell line

ABC-KD15834 AcceGen 1 vial Ask for price
Description: Human TNFRSF10D knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human TNFRSF10D Protein Lysate 20ug

IHUTNFRSF10DPLLY20UG Innovative research each 213 EUR
Description: Human TNFRSF10D Protein Lysate 20ug

Mouse Monoclonal anti-human TNFRSF10D EC

hAP-0579 Angio Proteomie 100ug 250 EUR

TNFRSF10D

CSB-CL887006HU Cusabio 10 μg plasmid + 200μl Glycerol Ask for price

TNFRSF10D

cyt-1045 ProSpec Tany 1µg 60 EUR
Description: Recombinant Human TRAIL Receptor-4

TNFRSF10D

MBS8564238-01mLAF405L MyBiosource 0.1mL(AF405L) 565 EUR

TNFRSF10D

MBS8564238-01mLAF405S MyBiosource 0.1mL(AF405S) 565 EUR

TNFRSF10D

MBS8564238-01mLAF610 MyBiosource 0.1mL(AF610) 565 EUR

TNFRSF10D

MBS8564238-01mLAF635 MyBiosource 0.1mL(AF635) 565 EUR

TNFRSF10D

MBS8564238-02mL MyBiosource 0.2mL 345 EUR

Mouse anti Human TRAIL R4/CD264/TNFRSF10D Monoclonal Antibody

MBS2543373-006mL MyBiosource 0.06mL 250 EUR

Mouse anti Human TRAIL R4/CD264/TNFRSF10D Monoclonal Antibody

MBS2543373-012mL MyBiosource 0.12mL 370 EUR

Mouse anti Human TRAIL R4/CD264/TNFRSF10D Monoclonal Antibody

MBS2543373-02mL MyBiosource 0.2mL 550 EUR

Recombinant Human TNFRSF10D, His tagged

TNFRSF10D-3169H Creative BioMart 100 µg 454.4 EUR
Description: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

TNFRSF10D ELISA Kit (Human) (OKBB01434)

OKBB01434 Aviva Systems Biology 96 Wells 606 EUR
Description: Description of target: Decoy receptor 2 (DCR2), also known as TRAIL receptor 4 (TRAILR4) and tumor necrosis factor receptor superfamily member 10D (TNFRSF10D), is a human cell surface receptor of the TNF-receptor superfamily. It is mapped to 8p21.3. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplasmic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

TNFRSF10D ELISA Kit (Human) (OKCA02319)

OKCA02319 Aviva Systems Biology 96 Wells 913.2 EUR
Description: Description of target: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: 0.078 ng/mL

TNFRSF10D ELISA Kit (Human) (OKEH04990)

OKEH04990 Aviva Systems Biology 96 Wells 715.2 EUR
Description: Description of target: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL

Human TNFRSF10D Protein, Fc & His Tag

E40KMPH6272 EnoGene 20ug 495 EUR

Human TNFRSF10D Protein, Fc & His Tag

E40KMPH1572 EnoGene 20ug 495 EUR

TNFRSF10D antibody

38726 SAB 100ul 439 EUR

TNFRSF10D antibody

38726-100ul SAB 100ul 302.4 EUR

TNFRSF10D Antibody

35312 SAB 100ul 319 EUR

TNFRSF10D Antibody

35312-100ul SAB 100ul 302.4 EUR

TNFRSF10D Antibody

35312-50ul SAB 50ul 224.4 EUR

TNFRSF10D Antibody

ABD4811 Lifescience Market 100 ug 525.6 EUR

TNFRSF10D Antibody

CSB-PA031451- Cusabio each 402 EUR
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

TNFRSF10D Antibody

CSB-PA031451-100ul Cusabio 100ul 379.2 EUR
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

TNFRSF10D Antibody

1-CSB-PA023967GA01HU Cusabio
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  • 50ul
  • 150ul
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

TNFRSF10D Antibody

DF4811 Affbiotech 200ul 420 EUR

TNFRSF10D Antibody

DF4811-100ul Affinity Biosciences 100ul 168 EUR
Description: WB,IF/ICC,ELISA(peptide)

TNFRSF10D Antibody

DF4811-200ul Affinity Biosciences 200ul 210 EUR
Description: WB,IF/ICC,ELISA(peptide)

TNFRSF10D Antibody

1-CSB-PA057438 Cusabio
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  • 50ul
  • 100ul
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

TNFRSF10D Antibody

1-CSB-PA070147 Cusabio
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  • 50ug
  • 100ug
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000

TNFRSF10D Antibody

1-CSB-PA08209A0Rb Cusabio
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  • 100ug
  • 50ug
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

TNFRSF10D Antibody

1-CSB-PA909727 Cusabio
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  • 50ul
  • 100ul
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:100-1:300

TNFRSF10D Antibody

1-CSB-PA887006ESR1HU Cusabio
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  • 100ul
  • 50ul
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

TNFRSF10D Antibody

1-CSB-PA887006ESR2HU Cusabio
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  • 100ul
  • 50ul
Description: A polyclonal antibody against TNFRSF10D. Recognizes TNFRSF10D from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

TNFRSF10D Antibody

E11-21301C EnoGene 100μg 225 EUR
Description: Available in various conjugation types.

TNFRSF10D Antibody

E035312 EnoGene 100μg/100μl 255 EUR
Description: Available in various conjugation types.

TNFRSF10D Antibody

E300301a EnoGene 100ug/200ul 295 EUR
Description: Available in various conjugation types.

TNFRSF10D Antibody

E312432 EnoGene 200ul 275 EUR
Description: Available in various conjugation types.

TNFRSF10D Antibody

E19-4811 EnoGene 100μg/100μl 225 EUR
Description: Available in various conjugation types.

TNFRSF10D Antibody

MBS2516914-006mL MyBiosource 0.06mL 190 EUR

TNFRSF10D Antibody

MBS2516914-012mL MyBiosource 0.12mL 265 EUR

TNFRSF10D Antibody

MBS2516914-02mL MyBiosource 0.2mL 415 EUR

TNFRSF10D Antibody

MBS2516914-5x02mL MyBiosource 5x0.2mL 1835 EUR

TNFRSF10D Antibody

MBS7131835-01mL MyBiosource 0.1mL 270 EUR

TNFRSF10D Antibody

MBS7131835-5x01mL MyBiosource 5x0.1mL 1200 EUR

TNFRSF10D Antibody

MBS7125425-005mL MyBiosource 0.05mL 190 EUR

TNFRSF10D Antibody

MBS7125425-01mL MyBiosource 0.1mL 270 EUR

TNFRSF10D Antibody

MBS7125425-5x01mL MyBiosource 5x0.1mL 1205 EUR

TNFRSF10D Antibody

MBS7125426-005mL MyBiosource 0.05mL 190 EUR

TNFRSF10D Antibody

MBS7125426-01mL MyBiosource 0.1mL 270 EUR

TNFRSF10D Antibody

MBS7125426-5x01mL MyBiosource 5x0.1mL 1205 EUR

TNFRSF10D Antibody

MBS7121152-005mg MyBiosource 0.05mg 150 EUR

TNFRSF10D Antibody

MBS7121152-01mg MyBiosource 0.1mg 190 EUR

TNFRSF10D Antibody

MBS7121152-5x01mg MyBiosource 5x0.1mg 845 EUR

TNFRSF10D Antibody

MBS8515514-01mg MyBiosource 0.1mg 305 EUR

TNFRSF10D Antibody

MBS8515514-01mLAF405L MyBiosource 0.1mL(AF405L) 465 EUR

TNFRSF10D Antibody

MBS8515514-01mLAF405S MyBiosource 0.1mL(AF405S) 465 EUR

TNFRSF10D Antibody

MBS8515514-01mLAF610 MyBiosource 0.1mL(AF610) 465 EUR

TNFRSF10D Antibody

MBS8515514-01mLAF635 MyBiosource 0.1mL(AF635) 465 EUR

TNFRSF10D Antibody

MBS9606265-01mL MyBiosource 0.1mL 260 EUR

TNFRSF10D Antibody

MBS9606265-02mL MyBiosource 0.2mL 305 EUR

TNFRSF10D Antibody

MBS9606265-5x02mL MyBiosource 5x0.2mL 1220 EUR

TNFRSF10D Antibody

MBS9510329-005mL MyBiosource 0.05mL 285 EUR

TNFRSF10D Antibody

MBS9510329-01mL MyBiosource 0.1mL 385 EUR

TNFRSF10D Antibody

MBS9510329-5x01mL MyBiosource 5x0.1mL 1590 EUR

TNFRSF10D Antibody

MBS856336-01mg MyBiosource 0.1mg 305 EUR

TNFRSF10D Antibody

MBS856336-01mLAF405L MyBiosource 0.1mL(AF405L) 465 EUR

TNFRSF10D Antibody

MBS856336-01mLAF405S MyBiosource 0.1mL(AF405S) 465 EUR

TNFRSF10D Antibody

MBS856336-01mLAF610 MyBiosource 0.1mL(AF610) 465 EUR

TNFRSF10D Antibody

MBS856336-01mLAF635 MyBiosource 0.1mL(AF635) 465 EUR

TNFRSF10D antibody

MBS9405762-005mL MyBiosource 0.05mL 300 EUR

TNFRSF10D antibody

MBS9405762-01mL MyBiosource 0.1mL 390 EUR

TNFRSF10D antibody

MBS9405762-5x01mL MyBiosource 5x0.1mL 1610 EUR

TNFRSF10D Antibody

MBS9507250-005mL MyBiosource 0.05mL 285 EUR

TNFRSF10D Antibody

MBS9507250-01mL MyBiosource 0.1mL 385 EUR

TNFRSF10D Antibody

MBS9507250-5x01mL MyBiosource 5x0.1mL 1590 EUR

TNFRSF10D Antibody

MBS9407376-005mL MyBiosource 0.05mL 245 EUR

TNFRSF10D Antibody

MBS9407376-01mL MyBiosource 0.1mL 305 EUR

TNFRSF10D Antibody

MBS9407376-5x01mL MyBiosource 5x0.1mL 1230 EUR

Anti-TRAIL-R4 TNFRSF10D Antibody

A05136 BosterBio 100ug 607 EUR
Description: Boster Bio Anti-TRAIL-R4 TNFRSF10D Antibody (Catalog# A05136). Tested in ICC, IHC, WB application(s). This antibody reacts with Human, Mouse, Rat.

DcR2 (TNFRSF10D) (NM_003840) Human Over-expression Lysate

E45H19123-2 EnoGene 20 ug 395 EUR

DcR2 (TNFRSF10D) (NM_003840) Human Over-expression Lysate

LS008793 BosterBio 100ug 628 EUR
Description: Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D)

Human DCR2/TNFRSF10D PicoKine ELISA Kit

MBS1752672-5x96StripWells MyBiosource 5x96-Strip-Wells 2755 EUR

Human DCR2/TNFRSF10D PicoKine ELISA Kit

MBS1752672-96StripWells MyBiosource 96-Strip-Wells 600 EUR

Recombinant Human TNFRSF10D, Fc-His tagged

TNFRSF10D-885H Creative BioMart 100 µg 454.4 EUR
Description: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Recombinant Human TNFRSF10D/TRAIL R4 Protein

RP00814 Abclonal 10μg 85.02 EUR

OKBB01434-96W - TNFRSF10D ELISA Kit (Human)

OKBB01434-96W Aviva Systems Biology 96wells 538 EUR

OKCA02319-96W - TNFRSF10D ELISA Kit (Human)

OKCA02319-96W Aviva Systems Biology 96Wells 600 EUR

OKEH04990-96W - TNFRSF10D ELISA Kit (Human)

OKEH04990-96W Aviva Systems Biology 96Wells 475 EUR

Human CellExp? TNFRSF10D / TRAIL R4, human recombinant

P1140-10 Biovision each 157.2 EUR

Human CellExp? TNFRSF10D / TRAIL R4, human recombinant

P1140-50 Biovision each 470.4 EUR

Human TRAIL R4 / TNFRSF10D Protein, His Tag

TR4-H52H5 ACROBIOSYSTEMS 1mg 272.5 EUR
Description: Human TRAIL R4, His Tag (TR4-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 56 - His 211 (Accession # NP_003831).

TNFRSF10D sgRNA CRISPR Lentivector set (Human)

K2415801 ABM 3 x 1.0 ug 406.8 EUR

Human TRAIL R4/TNFRSF10D Recombinant Protein

PROTQ9UBN6 BosterBio 10ug 265 EUR
Description: Human TRAIL R4/TNFRSF10D Recombinant Protein expressed in Baculovirus with hIgG-His-tag. Sequence domain: 56-211aa. Application(s): SDS-PAGE, Bioactivity. Endotoxin: < 1 EU per 1ug of protein (determined by LAL method).

TNFRSF10D Antibody Pair

CSB-EAP08209-1pair596wellplates Cusabio 1 pair(5*96 well plates) Ask for price
Description: We recommend using the capture antibody at a concentration of 0.5ug/ml and the detection antibody at a concentration of 0.25ug/ml.Optimal dilutions should be determined experimentally by the researcher.

TNFRSF10D Antibody Pair

CSB-EAP08209-each Cusabio each Ask for price
Description: We recommend using the capture antibody at a concentration of 0.5ug/ml and the detection antibody at a concentration of 0.25ug/ml.Optimal dilutions should be determined experimentally by the researcher.

TNFRSF10D Antibody Pair

MBS7041926-1PairSufficientfor5x96wellplates MyBiosource 1Pair(Sufficientfor5x96wellplates) 775 EUR

TNFRSF10D Antibody Pair

MBS7041926-5x1PairSufficientfor25x96wellplates MyBiosource 5x1Pair(Sufficientfor25x96wellplates) 3475 EUR

Human DCR2/TNFRSF10D ELISA Kit PicoKine®

EK2067 BosterBio 96 wells 499 EUR
Description: Human DCR2/TNFRSF10D ELISA Kit PicoKine® (96 Tests). Quantitate Human TNFRSF10D in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml.

TNFRSF10D Antibody (Center)

E45R06175G-1 EnoGene 100 ul 395 EUR

TNFRSF10D Antibody (Center)

E45R06175G-4 EnoGene 50 ul 295 EUR

TNFRSF10D Antibody (Center)

MBS9211624-008mL MyBiosource 0.08mL 210 EUR

TNFRSF10D Antibody (Center)

MBS9211624-04mL MyBiosource 0.4mL 430 EUR

TNFRSF10D Antibody (Center)

MBS9211624-5x04mL MyBiosource 5x0.4mL 1910 EUR

OOCA01712-25T - Human TNFRSF10D Primer Pair 1

OOCA01712-25T Aviva Systems Biology 25Tests 229 EUR

OOCA01713-25T - Human TNFRSF10D Primer Pair 2

OOCA01713-25T Aviva Systems Biology 25Tests 229 EUR

Human Decoy Receptor 2 (TNFRSF10D) ELISA Kit

IHUTNFRSF10DKT Innovative research each 702 EUR
Description: Human Decoy Receptor 2 (TNFRSF10D) ELISA Kit

Human Decoy Receptor 2 (TNFRSF10D) ELISA Kit

MBS8420084-1Kit MyBiosource 1Kit 755 EUR

Human Decoy Receptor 2 (TNFRSF10D) ELISA Kit

MBS8420084-5x1Kit MyBiosource 5x1Kit 3455 EUR

TNFRSF10D Protein Vector (Human) (pPM-C-HA)

PV043223 ABM 500 ng 394.8 EUR

TNFRSF10D Protein Vector (Human) (pPB-C-His)

PV043221 ABM 500 ng 394.8 EUR

TNFRSF10D Protein Vector (Human) (pPB-N-His)

PV043222 ABM 500 ng 394.8 EUR

TNFRSF10D Protein Vector (Human) (pPM-C-His)

PV043224 ABM 500 ng 394.8 EUR

TNFRSF10D Polyclonal Antibody

A54081 EpiGentek
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  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

TNFRSF10D Polyclonal Antibody

A71327 EpiGentek
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  • 50 ul
  • 100 ul

TNFRSF10D Polyclonal Antibody

A71328 EpiGentek
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  • 50 ul
  • 100 ul

TNFRSF10D polyclonal antibody

BS7929 Bioworld Biotech 50 ul 358 EUR
Description: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

TNFRSF10D Polyclonal Antibody

E-AB-61175-120uL Elabscience Biotech 120uL 320 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-61175-200uL Elabscience Biotech 200uL 530 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-61175-60uL Elabscience Biotech 60uL 200 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-61175-each Elabscience Biotech each Ask for price
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-14934-120uL Elabscience Biotech 120uL 240 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-14934-200uL Elabscience Biotech 200uL 399 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-14934-20uL Elabscience Biotech 20uL 73 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-14934-60uL Elabscience Biotech 60uL 143 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-11141-120uL Elabscience Biotech 120uL 240 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-11141-200uL Elabscience Biotech 200uL 399 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-11141-20uL Elabscience Biotech 20uL 73 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-11141-60uL Elabscience Biotech 60uL 143 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-17834-120uL Elabscience Biotech 120uL 240 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-17834-200uL Elabscience Biotech 200uL 399 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-17834-20uL Elabscience Biotech 20uL 73 EUR
Description: Unconjugated

TNFRSF10D Polyclonal Antibody

E-AB-17834-60uL Elabscience Biotech 60uL 143 EUR
Description: Unconjugated

TNFRSF10D Conjugated Antibody

C35312 SAB 100ul 476.4 EUR

TNFRSF10D Polyclonal Antibody

E914078 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

TNFRSF10D Polyclonal Antibody

E96136 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

TNFRSF10D Polyclonal Antibody

MBS2517702-002mL MyBiosource 0.02mL 135 EUR

TNFRSF10D Polyclonal Antibody

MBS2517702-006mL MyBiosource 0.06mL 190 EUR

TNFRSF10D Polyclonal Antibody

MBS2517702-012mL MyBiosource 0.12mL 265 EUR

TNFRSF10D Polyclonal Antibody

MBS2517702-02mL MyBiosource 0.2mL 415 EUR

TNFRSF10D Polyclonal Antibody

MBS2517702-5x02mL MyBiosource 5x0.2mL 1835 EUR

TNFRSF10D Polyclonal Antibody

MBS2561627-002mL MyBiosource 0.02mL 140 EUR

TNFRSF10D Polyclonal Antibody

MBS2561627-006mL MyBiosource 0.06mL 180 EUR

TNFRSF10D Polyclonal Antibody

MBS2561627-012mL MyBiosource 0.12mL 260 EUR

TNFRSF10D Polyclonal Antibody

MBS2561627-02mL MyBiosource 0.2mL 405 EUR

TNFRSF10D Polyclonal Antibody

MBS2561627-5x02mL MyBiosource 5x0.2mL 1725 EUR

TNFRSF10D Polyclonal Antibody

MBS2559723-002mL MyBiosource 0.02mL 135 EUR

TNFRSF10D Polyclonal Antibody

MBS2559723-006mL MyBiosource 0.06mL 190 EUR
The marine polysaccharide-based DDS combines the benefits of polysaccharide supplies and nanotechnology, and is appropriate as a provider for completely different pharmaceutical preparations. This assessment summarizes the benefits and drawbacks of utilizing marine polysaccharides to assemble the NDDS and describes the preparation strategies and modification methods of marine polysaccharide-based nanocarriers.
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