Tag: pcr

Blocking HSV-1 glycoprotein K binding to signal peptide peptidase reduces virus infectivity in vitro and in vivo

HSV glycoprotein K (gK) is an important herpes protein that contributes to enhancement of eye illness. We beforehand reported that gK binds to signal peptide peptidase (SPP) and that depletion of SPP reduces HSV-1 infectivity in vivo. To decide the therapeutic potential of blocking gK binding to SPP on virus infectivity and pathogenicity, we mapped […]

Transcription Factors in Neurodevelopmental and Associated Psychiatric Disorders: A Potential Convergence for Genetic and Environmental Risk Factors
Transcription Factors in Neurodevelopmental and Associated Psychiatric Disorders: A Potential Convergence for Genetic and Environmental Risk Factors

Neurodevelopmental issues (NDDs) are a heterogeneous and extremely prevalent group of psychiatric situations marked by impairments in the nervous system. Their onset happens throughout gestation, and the alterations are noticed all through the postnatal life. Although many genetic and environmental danger elements have been described in this context, the interactions between them problem the understanding […]

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