Immunotherapies within the German healthcare system : Economic aspects of established antibodies and recently available therapies In the German healthcare system, immunotherapies have been effectively established for years. Currently there are over 100 registrations of monoclonal antibodies (MABs). In current years, new immunotherapeutic approaches turned available, amongst them checkpoint inhibitors and CAR‑T cells in oncology. […]
Impact of Immune Priming, Vaccination and Infection on Influenza A(H3N2) Antibody Landscapes in Children Background: Pre-existing antibodies to influenza, formed by early an infection and subsequent exposures, might affect responses to influenza vaccination. Methods: We enrolled 72 youngsters (7-17 years) in 2015-16, all obtained inactivated influenza vaccines. Forty-one have been additionally vaccinated in 2014-15 with 12 grew to become […]
Systemic phenotype associated to major Sjögren’s syndrome in 279 sufferers carrying remoted anti-La/SSB antibodies Objectives: To consider the systemic phenotype related to the presence of remoted anti-La/SSB antibodies in a big worldwide registry of sufferers with major Sjögren’s syndrome (pSS) fulfilling the 2002 classification standards. Methods: The Big Data Sjögren Project Consortium is a world, multicentre […]
Moxifloxacin-Induced Thrombocytopenia Mediated by Moxifloxacin-Dependent IgM and IgG Antiplatelet Antibodies: A Case Report Moxifloxacin is a rare but important cause of drug-induced immune thrombocytopenia (DIT). We describe a patient who presented with an acute onset of severe thrombocytopenia complicated by petechial rash, epistaxis, and melena. Recent new drug exposures included moxifloxacin and two proton pump […]
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