Tag: ELISA kit

Blocking HSV-1 glycoprotein K binding to signal peptide peptidase reduces virus infectivity in vitro and in vivo

HSV glycoprotein K (gK) is an important herpes protein that contributes to enhancement of eye illness. We beforehand reported that gK binds to signal peptide peptidase (SPP) and that depletion of SPP reduces HSV-1 infectivity in vivo. To decide the therapeutic potential of blocking gK binding to SPP on virus infectivity and pathogenicity, we mapped […]

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